(E)-(4S,5R,6S)-5-Benzyloxy-6-(2,2-dimethyl-[1,3]dioxolan-4-yl)-4,6-dimethoxy-2-methyl-hex-2-enoic acid methyl ester

Base Information

Chemical Name:(E)-(4S,5R,6S)-5-Benzyloxy-6-(2,2-dimethyl-[1,3]dioxolan-4-yl)-4,6-dimethoxy-2-methyl-hex-2-enoic acid methyl ester
CAS No.:118299-05-1
Molecular Formula:C₂₂H₃₂O₇
Molecular Weight:408.492
Hs Code.:

Synonyms:(E)-(4S,5R,6S)-5-Benzyloxy-6-(2,2-dimethyl-[1,3]dioxolan-4-yl)-4,6-dimethoxy-2-methyl-hex-2-enoic acid methyl ester

Suppliers and Price of (E)-(4S,5R,6S)-5-Benzyloxy-6-(2,2-dimethyl-[1,3]dioxolan-4-yl)-4,6-dimethoxy-2-methyl-hex-2-enoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-(4S,5R,6S)-5-Benzyloxy-6-(2,2-dimethyl-[1,3]dioxolan-4-yl)-4,6-dimethoxy-2-methyl-hex-2-enoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-(4S,5R,6S)-5-Benzyloxy-6-(2,2-dimethyl-[1,3]dioxolan-4-yl)-4,6-dimethoxy-2-methyl-hex-2-enoic acid methyl ester

There total 5 articles about (E)-(4S,5R,6S)-5-Benzyloxy-6-(2,2-dimethyl-[1,3]dioxolan-4-yl)-4,6-dimethoxy-2-methyl-hex-2-enoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 126502-45-2
(3S,4R,5S)-4-Benzyloxy-3,5-dimethoxy-hexane-1,2,6-triol

: 118299-05-1
(E)-(4S,5R,6S)-5-Benzyloxy-6-(2,2-dimethyl-[1,3]dioxolan-4-yl)-4,6-dimethoxy-2-methyl-hex-2-enoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / TsOH, 3-A molecular sieves / Ambient temperature

2: (ClCO)2, DMSO, TEA / CH₂Cl₂ / -78 °C

3: CH₂Cl₂ / from 0 deg C to RT

With oxalyl dichloride; 3 A molecular sieve; TEA; toluene-4-sulfonic acid; dimethyl sulfoxide; In dichloromethane;
DOI:10.1021/jo00262a006

Reference yield:

: 126502-46-3
(2S,3R,4S)-3-Benzyloxy-4-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4-dimethoxy-butan-1-ol

: 118299-05-1
(E)-(4S,5R,6S)-5-Benzyloxy-6-(2,2-dimethyl-[1,3]dioxolan-4-yl)-4,6-dimethoxy-2-methyl-hex-2-enoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: (ClCO)2, DMSO, TEA / CH₂Cl₂ / -78 °C

2: CH₂Cl₂ / from 0 deg C to RT

With oxalyl dichloride; TEA; dimethyl sulfoxide; In dichloromethane;
DOI:10.1021/jo00262a006

Reference yield:

: 126502-45-2
2,4-Di-O-methyl-3-O-(phenylmethyl)-D-galactol

: 118299-05-1
(2E)-2,3-Dideoxy-2-methyl-4,6-di-O-methyl-7,8-O-(1-methylethylidene)-5-O-(phenylmethyl)-D-galacto-oct-2-enonic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / p-TsOH, molecular sieves / 4 h / Ambient temperature

2: 1) DMSO, oxalyl chloride 2) Et₃N / 1) CH₂Cl₂, 20 min, -78 deg C 2) 25 min without cooling

3: CH₂Cl₂ / 12 h / Ambient temperature

With molecular sieve; oxalyl dichloride; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine; In dichloromethane;
DOI:10.1021/jo00296a041