Technology Process of N-(3-butyramidophenyl)-3-chlorobenzamide
There total 3 articles about N-(3-butyramidophenyl)-3-chlorobenzamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
3-butyrylaminoaniline; 3-chlorobenzoate;
With
benzotriazol-1-ol; dicyclohexyl-carbodiimide;
In
dichloromethane;
for 15h;
Sealed tube;
With
trimethylammonium carbonate;
In
dichloromethane; acetonitrile;
for 1h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 16 h / Sealed tube; Inert atmosphere; Cooling with ice
2.1: 5%-palladium/activated carbon; hydrogen / methanol / 16 h
3.1: benzotriazol-1-ol; dicyclohexyl-carbodiimide / dichloromethane / 15 h / Sealed tube
3.2: 1 h
With
5%-palladium/activated carbon; hydrogen; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide;
In
methanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 5%-palladium/activated carbon; hydrogen / methanol / 16 h
2.1: benzotriazol-1-ol; dicyclohexyl-carbodiimide / dichloromethane / 15 h / Sealed tube
2.2: 1 h
With
5%-palladium/activated carbon; hydrogen; benzotriazol-1-ol; dicyclohexyl-carbodiimide;
In
methanol; dichloromethane;
