C₂₅H₂₇NO₇

Base Information

• Chemical Name: C₂₅H₂₇NO₇
• CAS No.: 1391850-04-6
• Molecular Formula: C₂₅H₂₇NO₇
• Molecular Weight: 453.492
• Mol file: 1391850-04-6.mol

Synonyms:C₂₅H₂₇NO₇

Chemical Property of C₂₅H₂₇NO₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₂₇NO₇

There total 4 articles about C₂₅H₂₇NO₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C41H45NO7Si → C25H27NO7 (1391850-04-6)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; stereoselective reaction;

DOI:10.1002/chem.201103015

Reference yield:

diethyl (3S,4R,5R,1'E)-4-formyl-3-phenyl-5-styrylpyrrolidine-2,2-dicarboxylate (1391849-75-4) → C25H27NO7 (1391850-04-6)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium tetrahydroborate / methanol / 0.5 h / 0 °C

2.1: 1H-imidazole; dmap / tetrahydrofuran / 20 °C

3.1: potassium carbonate / acetonitrile / 2 h / Reflux

3.2: 2 h / Reflux

4.1: ozone / dichloromethane / -78 °C

4.2: 1 h / -78 °C

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C

With 1H-imidazole; dmap; sodium tetrahydroborate; tetrabutyl ammonium fluoride; potassium carbonate; ozone; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;

DOI:10.1002/chem.201103015

Reference yield:

diethyl (3S,4R,5R,1'E)-4-[(tertbutyldiphenylsilyloxy)methyl]-3-phenyl-5-styrylpyrrolidine-2,2-dicarboxylate (1391849-91-4) → C25H27NO7 (1391850-04-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium carbonate / acetonitrile / 2 h / Reflux

1.2: 2 h / Reflux

2.1: ozone / dichloromethane / -78 °C

2.2: 1 h / -78 °C

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C

With tetrabutyl ammonium fluoride; potassium carbonate; ozone; In tetrahydrofuran; dichloromethane; acetonitrile;

DOI:10.1002/chem.201103015

upstream raw materials:

diethyl (3S,4R,5R,1'E)-4-formyl-3-phenyl-5-styrylpyrrolidine-2,2-dicarboxylate

diethyl (3S,4R,5R,1'E)-4-[(tertbutyldiphenylsilyloxy)methyl]-3-phenyl-5-styrylpyrrolidine-2,2-dicarboxylate

diethyl (3S,4R,5R,1'E)-1-benzoyl-4-[(tertbutyldiphenylsilyloxy)methyl]-3-phenyl-5-styrylpyrrolidine-2,2-dicarboxylate

Downstream raw materials:

diethyl (3S,3aR,6aS)-1-benzoyl-6-oxo-3-phenyltetrahydro-1H-furo[3,4-b]pyrrole-2,2(3H)-dicarboxylate

diethyl (3S,3aR,6aS)-1-benzoyl-3-phenyltetrahydro-1H-furo[3,4-b]pyrrole-2,2(3H)-dicarboxylate