(R)-Roemerine

Base Information Edit

Chemical Name:(R)-Roemerine
CAS No.:548-08-3
Molecular Formula:C18H17 N O2
Molecular Weight:279.338
Hs Code.:
NSC Number:36335
DSSTox Substance ID:DTXSID10866578
Nikkaji Number:J39.856J
Wikidata:Q104396030
Metabolomics Workbench ID:44290
ChEMBL ID:CHEMBL36654
Mol file:548-08-3.mol

Synonyms:Aporheine;Remerine;(R)-Roemerine;GNF-PF-4466;Remerin;CHEMBL36654;2030-53-7;(-)-roemerine;15548-23-9;Roemerin;11-methyl-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1(20),2(6),7,14,16,18-hexaene;l-Roemerine;(-)-Aporheine;Remerine (alkaloid);6,7,7a,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline;SR-01000810842;1-Remerine;(-)-Remerine;ST082313;Oprea1_656488;Oprea1_838512;MLS001208416;SCHEMBL673805;cid_235224;ACon1_001394;DTXSID10866578;CHEBI:173982;HMS1692H22;NSC36335;BDBM50284797;NSC-36335;STL560632;AKOS024285186;1,2-(Methylenedioxy)-6a-beta-Aporphine;NCGC00180552-01;SMR000517937;FT-0775728;SR-01000810842-2;SR-01000810842-3;SR-01000810842-4;7-Methyl-6,7,7a,8-tetrahydro-2H,5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline;7-Methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline;(12S)-11-methyl-3,5-dioxa-11-azapentacyclo[10.7.1.0^{2,6.0^{8,20.0^{14,19]icosa-1(20),2(6),7,14,16,18-hexaene;11-methyl-3,5-dioxa-11-azapentacyclo[10.7.1.0?,?.0?,??.0??,??]icosa-1(20),2(6),7,14,16,18-hexaene;11-methyl-3,5-dioxa-11-azapentacyclo[10.7.1.0^{2,6}.0^{8,20}.0^{14,19}]icosa-1(20),2(6),7,14,16,18-hexaene;7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4'',5'':4,5]benzo[1,2,3-de]quinoline;7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline

Suppliers and Price of (R)-Roemerine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Roemerine
10mg
$ 1320.00

AvaChem
Roemerine
10mg
$ 490.00

AvaChem
Roemerine
5mg
$ 290.00

AvaChem
Roemerine
1mg
$ 119.00

AvaChem
Roemerine
20mg
$ 690.00

American Custom Chemicals Corporation
ROEMERINE 95.00%
5MG
$ 499.97

Total 14 raw suppliers

Chemical Property of (R)-Roemerine Edit

Chemical Property:

Vapor Pressure:2.13E-07mmHg at 25°C
Melting Point:102-103℃
Boiling Point:424°Cat760mmHg
PKA:7.87±0.20(Predicted)
Flash Point:162.4°C
PSA：21.70000
Density:1.269g/cm³
LogP:3.10530
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:279.125928785
Heavy Atom Count:21
Complexity:414

Purity/Quality:

99%, ^*data from raw suppliers

Roemerine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC2=CC3=C(C4=C2C1CC5=CC=CC=C54)OCO3
Uses Roemerine is an (-)-aporphine type of alkaloid which has been shown to possess significant antibacterial activity against Escheria Coli.

Technology Process of (R)-Roemerine

There total 15 articles about (R)-Roemerine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: (S)-methyl 7a,8-dihydro-5H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]benzo[g]quinoline-7(6H)-carboxylate

: 548-08-3,2030-53-7,15548-23-9
(+)-roemerine

Guidance literature:: (S)-methyl 7a,8-dihydro-5H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]benzo[g]quinoline-7(6H)-carboxylate; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 24h; Inert atmosphere;

With water; In tetrahydrofuran; at 20 ℃;
DOI:10.1039/c7md00629b