diisopropyl [(2-hydroxy-3-tosyloxypropoxy)methyl]phosphonate

Base Information

• Chemical Name: diisopropyl [(2-hydroxy-3-tosyloxypropoxy)methyl]phosphonate
• CAS No.: 1233765-60-0
• Molecular Formula: C₁₇H₂₉O₈PS
• Molecular Weight: 424.452
• Mol file: 1233765-60-0.mol

Synonyms:diisopropyl [(2-hydroxy-3-tosyloxypropoxy)methyl]phosphonate

Chemical Property of diisopropyl [(2-hydroxy-3-tosyloxypropoxy)methyl]phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diisopropyl [(2-hydroxy-3-tosyloxypropoxy)methyl]phosphonate

There total 1 articles about diisopropyl [(2-hydroxy-3-tosyloxypropoxy)methyl]phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

C10H23O6P (1233765-59-7) + p-toluenesulfonyl chloride (98-59-9) → diisopropyl [(2-hydroxy-3-tosyloxypropoxy)methyl]phosphonate (1233765-60-0)

Guidance literature:

With pyridine; dmap; at 0 - 20 ℃; Cooling;

DOI:10.1135/cccc2009569

Reference yield: 62.0%

3,4-dihydro-2H-pyran (110-87-2) + diisopropyl [(2-hydroxy-3-tosyloxypropoxy)methyl]phosphonate (1233765-60-0) → diisopropyl {[2-(tetrahydro-2-pyranyl)oxy-3-tosyloxypropoxy]methyl}phosphonate (1233765-61-1)

Guidance literature:

With hydrogenchloride; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

DOI:10.1135/cccc2009569

upstream raw materials:

C₁₀H₂₃O₆P

p-toluenesulfonyl chloride

Downstream raw materials:

diisopropyl {[2-(tetrahydro-2-pyranyl)oxy-3-tosyloxypropoxy]methyl}phosphonate