N-benzyl-4-(4-chlorophenyl)-4-oxobutanamide

Base Information

Chemical Name:N-benzyl-4-(4-chlorophenyl)-4-oxobutanamide
CAS No.:64081-79-4
Molecular Formula:C₁₇H₁₆ClNO₂
Molecular Weight:301.773
Hs Code.:
DSSTox Substance ID:DTXSID401328621
ChEMBL ID:CHEMBL1704187

Synonyms:N-benzyl-4-(4-chlorophenyl)-4-oxobutanamide;MLS001030723;CHEMBL1704187;SCHEMBL10771939;DTXSID401328621;HMS2953D09;AKOS002123107;SMR000635265;AB00719409-01;Z27749650;64081-79-4

Suppliers and Price of N-benzyl-4-(4-chlorophenyl)-4-oxobutanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-benzyl-4-(4-chlorophenyl)-4-oxobutanamide

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:301.0869564
Heavy Atom Count:21
Complexity:345

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CNC(=O)CCC(=O)C2=CC=C(C=C2)Cl

Technology Process of N-benzyl-4-(4-chlorophenyl)-4-oxobutanamide

There total 5 articles about N-benzyl-4-(4-chlorophenyl)-4-oxobutanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 170805-90-0
(Z)-4-(4-Chloro-phenyl)-4-hydroxy-but-2-enoic acid benzylamide

: 64081-79-4
N-benzyl-3-(p-chlorobenzoyl)propionamide

Guidance literature:: In toluene; for 6h; Heating;

Reference yield:

: 104-88-1
4-chlorobenzaldehyde

: 64081-79-4
N-benzyl-3-(p-chlorobenzoyl)propionamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) LDA / 1.) THF, hexane, -20 deg C, 1 h, 2.) THF, hexane, -20 deg C, 30 min

2: H₂ / Pd/CaCO₃ / ethanol / 760 Torr

3: 83 percent / toluene / 6 h / Heating

With hydrogen; lithium diisopropyl amide; Lindlar's catalyst; In ethanol; toluene;

Reference yield:

: 87605-11-6
propynoic acid benzylamide

: 64081-79-4
N-benzyl-3-(p-chlorobenzoyl)propionamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) LDA / 1.) THF, hexane, -20 deg C, 1 h, 2.) THF, hexane, -20 deg C, 30 min

2: H₂ / Pd/CaCO₃ / ethanol / 760 Torr

3: 83 percent / toluene / 6 h / Heating

With hydrogen; lithium diisopropyl amide; Lindlar's catalyst; In ethanol; toluene;