N₁-[(3-{[3-{[(5-chloro-2-thienyl)sulfonyl]amino}-4-(methyloxy)-1H-indazol-1-yl]methyl}phenyl)methyl]-N₂-methyl-L-alaninamide trifluoroacetate

Base Information

• Chemical Name: N₁-[(3-{[3-{[(5-chloro-2-thienyl)sulfonyl]amino}-4-(methyloxy)-1H-indazol-1-yl]methyl}phenyl)methyl]-N₂-methyl-L-alaninamide trifluoroacetate
• CAS No.: 1240516-08-8
• Molecular Formula: C₂HF₃O₂*C₂₄H₂₆ClN₅O₄S₂
• Molecular Weight: 662.11

Synonyms:N₁-[(3-{[3-{[(5-chloro-2-thienyl)sulfonyl]amino}-4-(methyloxy)-1H-indazol-1-yl]methyl}phenyl)methyl]-N₂-methyl-L-alaninamide trifluoroacetate

Chemical Property of N₁-[(3-{[3-{[(5-chloro-2-thienyl)sulfonyl]amino}-4-(methyloxy)-1H-indazol-1-yl]methyl}phenyl)methyl]-N₂-methyl-L-alaninamide trifluoroacetate

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Technology Process of N₁-[(3-{[3-{[(5-chloro-2-thienyl)sulfonyl]amino}-4-(methyloxy)-1H-indazol-1-yl]methyl}phenyl)methyl]-N₂-methyl-L-alaninamide trifluoroacetate

There total 1 articles about N₁-[(3-{[3-{[(5-chloro-2-thienyl)sulfonyl]amino}-4-(methyloxy)-1H-indazol-1-yl]methyl}phenyl)methyl]-N₂-methyl-L-alaninamide trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-[1-{[3-(aminomethyl)phenyl]methyl}-4-(methyloxy)-1H-indazol-3-yl]-5-chloro-2-thiophenesulfonamide (1240518-83-5) + N-(tert-butoxycarbonyl)-N-methyl-L-alanine (16948-16-6) → N1-[(3-{[3-{[(5-chloro-2-thienyl)sulfonyl]amino}-4-(methyloxy)-1H-indazol-1-yl]methyl}phenyl)methyl]-N2-methyl-L-alaninamide trifluoroacetate (1240516-08-8)

Guidance literature:

N-(tert-butoxycarbonyl)-N-methyl-L-alanine; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide;

N-[1-{[3-(aminomethyl)phenyl]methyl}-4-(methyloxy)-1H-indazol-3-yl]-5-chloro-2-thiophenesulfonamide; In N,N-dimethyl-formamide; at 20 ℃; for 72h;

upstream raw materials:

N-[1-{[3-(aminomethyl)phenyl]methyl}-4-(methyloxy)-1H-indazol-3-yl]-5-chloro-2-thiophenesulfonamide

N-(tert-butoxycarbonyl)-N-methyl-L-alanine

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