19-bromo-2,3,4,5-tetrahydro-1,3,3-trimethyl-10-(4-methylphenyl)-15-[4-[2-(trimethylsilyl)ethoxycarbonyl]phenyl]bilene-a

Base Information

Chemical Name:19-bromo-2,3,4,5-tetrahydro-1,3,3-trimethyl-10-(4-methylphenyl)-15-[4-[2-(trimethylsilyl)ethoxycarbonyl]phenyl]bilene-a
CAS No.:378751-02-1
Molecular Formula:C₄₁H₄₉BrN₄O₂Si
Molecular Weight:737.855
Hs Code.:

Synonyms:19-bromo-2,3,4,5-tetrahydro-1,3,3-trimethyl-10-(4-methylphenyl)-15-[4-[2-(trimethylsilyl)ethoxycarbonyl]phenyl]bilene-a

Suppliers and Price of 19-bromo-2,3,4,5-tetrahydro-1,3,3-trimethyl-10-(4-methylphenyl)-15-[4-[2-(trimethylsilyl)ethoxycarbonyl]phenyl]bilene-a

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 19-bromo-2,3,4,5-tetrahydro-1,3,3-trimethyl-10-(4-methylphenyl)-15-[4-[2-(trimethylsilyl)ethoxycarbonyl]phenyl]bilene-a

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 19-bromo-2,3,4,5-tetrahydro-1,3,3-trimethyl-10-(4-methylphenyl)-15-[4-[2-(trimethylsilyl)ethoxycarbonyl]phenyl]bilene-a

There total 7 articles about 19-bromo-2,3,4,5-tetrahydro-1,3,3-trimethyl-10-(4-methylphenyl)-15-[4-[2-(trimethylsilyl)ethoxycarbonyl]phenyl]bilene-a which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 276239-53-3
2-[(3,3,5-trimethyl-3,4-dihydro-2H-pyrrol-2-yl)methyl]pyrrole

: 475560-29-3
4-{(5-bromo-1H-pyrrol-2-yl)-[5-(hydroxy-p-tolyl-methyl)-1H-pyrrol-2-yl]-methyl}-benzoic acid 2-trimethylsilanyl-ethyl ester

: 378751-02-1
19-bromo-2,3,4,5-tetrahydro-1,3,3-trimethyl-10-(4-methylphenyl)-15-[4-[2-(trimethylsilyl)ethoxycarbonyl]phenyl]bilene-a

Guidance literature:: With trifluoroacetic acid; In acetonitrile; at 20 ℃; for 0.5h;
DOI:10.1021/jo0104835

Reference yield:

: 74032-45-4
S-2-pyridyl 4-methylbenzothiolate

: 378751-02-1
19-bromo-2,3,4,5-tetrahydro-1,3,3-trimethyl-10-(4-methylphenyl)-15-[4-[2-(trimethylsilyl)ethoxycarbonyl]phenyl]bilene-a

Guidance literature:: Multi-step reaction with 4 steps

1: 54 percent / EtMgBr / tetrahydrofuran / 3 h / -78 °C

2: 81 percent / NBS / tetrahydrofuran / 1 h / -78 °C

3: NaBH₄ / tetrahydrofuran; methanol

4: 55 percent / TFA / acetonitrile / 0.5 h / 20 °C

With sodium tetrahydroborate; N-Bromosuccinimide; ethylmagnesium bromide; trifluoroacetic acid; In tetrahydrofuran; methanol; acetonitrile;
DOI:10.1021/jo0104835

Reference yield:

: 262267-30-1
5-[4-[2-(trimethylsilyl)ethoxycarbonyl]phenyl]dipyrromethane

: 378751-02-1
19-bromo-2,3,4,5-tetrahydro-1,3,3-trimethyl-10-(4-methylphenyl)-15-[4-[2-(trimethylsilyl)ethoxycarbonyl]phenyl]bilene-a

Guidance literature:: Multi-step reaction with 4 steps

1: 54 percent / EtMgBr / tetrahydrofuran / 3 h / -78 °C

2: 81 percent / NBS / tetrahydrofuran / 1 h / -78 °C

3: NaBH₄ / tetrahydrofuran; methanol

4: 55 percent / TFA / acetonitrile / 0.5 h / 20 °C

With sodium tetrahydroborate; N-Bromosuccinimide; ethylmagnesium bromide; trifluoroacetic acid; In tetrahydrofuran; methanol; acetonitrile;
DOI:10.1021/jo0104835