4-benzyloxy-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-7,7,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-triene

Base Information

Chemical Name:4-benzyloxy-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-7,7,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-triene
CAS No.:908864-78-8
Molecular Formula:C₃₀H₄₈O₆Si₂
Molecular Weight:560.879
Hs Code.:

4-benzyloxy-2,8-bis-(<i>tert</i>-butyl-dimethyl-silanyloxy)-7,7,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-triene

Synonyms:4-benzyloxy-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-7,7,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-triene

Suppliers and Price of 4-benzyloxy-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-7,7,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-triene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-benzyloxy-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-7,7,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-triene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-benzyloxy-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-7,7,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-triene

There total 9 articles about 4-benzyloxy-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-7,7,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-triene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 908864-71-1
trifluoro-methanesulfonic acid 5-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-2-iodo-phenyl ester

: 1-tert-butyldimethylsiloxy-1-methoxy-2,2-dimethoxyethylene

: 908864-78-8
4-benzyloxy-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-7,7,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-triene

Guidance literature:: With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 0.0833333h;
DOI:10.1021/ja064063e

Reference yield:

: 908864-75-5
5-benzyloxy-2-iodo-benzene-1,3-diol

: 908864-78-8
4-benzyloxy-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-7,7,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-triene

Guidance literature:: Multi-step reaction with 4 steps

1: 82.2 percent / N,N-diisopropylethylamine / CH₂Cl₂ / 0.25 h / -78 °C

2: 86.4 percent / cesium carbonate / 1,2-dimethoxy-ethane / 5 h / 90 °C

3: 96.3 percent / imidazole / dimethylformamide / 0.25 h / 25 °C

4: n-BuLi / diethyl ether; hexane / 0.08 h / -78 °C

With 1H-imidazole; n-butyllithium; caesium carbonate; N-ethyl-N,N-diisopropylamine; In 1,2-dimethoxyethane; diethyl ether; hexane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja064063e

Reference yield:

: 850399-67-6
1,3-di-O-acetyl-5-O-benzyl-benzophenone

: 908864-78-8
4-benzyloxy-2,8-bis-(tert-butyl-dimethyl-silanyloxy)-7,7,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-triene

Guidance literature:: Multi-step reaction with 6 steps

1: aq.NaOH / dioxane

2: 78.3 percent / KI; sodium hydrogencarbonate; iodine / tetrahydrofuran; H₂O / 1 h / 0 °C

3: 82.2 percent / N,N-diisopropylethylamine / CH₂Cl₂ / 0.25 h / -78 °C

4: 86.4 percent / cesium carbonate / 1,2-dimethoxy-ethane / 5 h / 90 °C

5: 96.3 percent / imidazole / dimethylformamide / 0.25 h / 25 °C

6: n-BuLi / diethyl ether; hexane / 0.08 h / -78 °C

With 1H-imidazole; sodium hydroxide; n-butyllithium; iodine; sodium hydrogencarbonate; caesium carbonate; N-ethyl-N,N-diisopropylamine; potassium iodide; In tetrahydrofuran; 1,4-dioxane; 1,2-dimethoxyethane; diethyl ether; hexane; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/ja064063e