(S)-tert-butyl 2-(4-bromophenyl)pyrrolidine-1-carboxylate

Base Information

Chemical Name:(S)-tert-butyl 2-(4-bromophenyl)pyrrolidine-1-carboxylate
CAS No.:1189152-81-5
Molecular Formula:C₁₅H₂₀BrNO₂
Molecular Weight:326.233
Hs Code.:
Mol file:1189152-81-5.mol

Synonyms:tert-butyl (S)-2-(4-bromophenyl)pyrrolidine-1-carboxylate

Suppliers and Price of (S)-tert-butyl 2-(4-bromophenyl)pyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Ambeed
(S)-tert-butyl2-(4-bromophenyl)pyrrolidine-1-carboxylate 95%
1g
$ 594.00

Ambeed
(S)-tert-butyl2-(4-bromophenyl)pyrrolidine-1-carboxylate 95%
250mg
$ 245.00

Ambeed
(S)-tert-butyl2-(4-bromophenyl)pyrrolidine-1-carboxylate 95%
100mg
$ 174.00

Total 9 raw suppliers

Chemical Property of (S)-tert-butyl 2-(4-bromophenyl)pyrrolidine-1-carboxylate

Chemical Property:

Boiling Point:382.9±42.0 °C(Predicted)
PKA:-2.25±0.40(Predicted)
Density:1.319±0.06 g/cm3(Predicted)
Storage Temp.:Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

(S)-tert-butyl2-(4-bromophenyl)pyrrolidine-1-carboxylate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-tert-butyl 2-(4-bromophenyl)pyrrolidine-1-carboxylate

There total 7 articles about (S)-tert-butyl 2-(4-bromophenyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: tert-butyl (4-bromobenzyl)(3-(2-tosylhydrazono)propyl)carbamate

: 1189152-81-5,328546-99-2
tert-butyl (S)-2-(4-bromophenyl)pyrrolidine-1-carboxylate

Guidance literature:: With C₇₀H₆₈CoN₈O₈; caesium carbonate; In 1,4-dioxane; at 60 ℃; for 24h; enantioselective reaction; Inert atmosphere; Schlenk technique;
DOI:10.1021/jacs.8b01662

Reference yield: 91.0%

: 24424-99-5
di-tert-butyl dicarbonate

: (S)-2-(4-bromo-phenyl)-pyrrolidine tartrate

: 1189152-81-5,328546-99-2
tert-butyl (S)-2-(4-bromophenyl)pyrrolidine-1-carboxylate

Guidance literature:: With 4-methyl-morpholine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 4h;

Reference yield:

: tert-butyl (4-bromobenzyl)(3-oxopropyl)carbamate

: 1189152-81-5,328546-99-2
tert-butyl (S)-2-(4-bromophenyl)pyrrolidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 0.5 h / 20 °C

2: caesium carbonate; C₇₀H₆₈CoN₈O₈ / 1,4-dioxane / 24 h / 60 °C / Inert atmosphere; Schlenk technique

With C₇₀H₆₈CoN₈O₈; caesium carbonate; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1021/jacs.8b01662