Technology Process of (1aR*,9-alpha,10-beta,10a-alpha)-10,10a-Dihydro-9H-fluorantheno(1,10b- beta)oxirene-9,10-diol
There total 7 articles about (1aR*,9-alpha,10-beta,10a-alpha)-10,10a-Dihydro-9H-fluorantheno(1,10b- beta)oxirene-9,10-diol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3-chloro-benzenecarboperoxoic acid;
In
chloroform;
at 0 ℃;
for 1h;
DOI:10.1021/jo00146a011
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 21 percent / NaBH4, O2 / ethanol / 48 h
2: 55 percent / m-chloroperbenzoic acid / tetrahydrofuran / 3 h
With
sodium tetrahydroborate; oxygen; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; ethanol;
DOI:10.1021/jo00240a013
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 84 percent / NaBH4 / methanol / 0 °C
2: 100 percent / p-toluenesulfonic acid / benzene / 2 h / Heating
3: 1.) I2 / 1.) C6H6, 2.) overnight
4: 48 percent / o-chloranil / dioxane / Heating; overnight
5: 83 percent / 1 N NaOMe / tetrahydrofuran; methanol / 1 h / -20 °C
6: 66 percent / 99percent m-chloroperoxybenzoic acid / CHCl3 / 1 h / 0 °C
With
sodium tetrahydroborate; o-tetrachloroquinone; iodine; sodium methylate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; 1,4-dioxane; methanol; chloroform; benzene;
DOI:10.1021/jo00146a011