(S)-3,4-diphenylbutanal

Base Information

• Chemical Name: (S)-3,4-diphenylbutanal
• CAS No.: 184483-51-0
• Molecular Formula: C₁₆H₁₆O
• Molecular Weight: 224.302
• Mol file: 184483-51-0.mol

Synonyms:(S)-3,4-diphenylbutanal

Chemical Property of (S)-3,4-diphenylbutanal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-3,4-diphenylbutanal

There total 11 articles about (S)-3,4-diphenylbutanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(S)-N-(tert-butoxycarbonyl)-N-(4-methoxyphenyl)-3,4-diphenyl-(Z)-1-buten-1-amine (184483-45-2) → (S)-3,4-diphenylbutanal (184483-51-0)

Guidance literature:

With hydrogenchloride; In chloroform;

DOI:10.1016/S0040-4039(00)01663-4

Reference yield: 96.0%

(3'S,4S)-3-(3',4'-diphenylbutyryl)-4-phenyl-5,5-dimethyloxazolidin-2-one (637330-79-1) → (S)-3,4-diphenylbutanal (184483-51-0)

Guidance literature:

With diisobutylaluminium hydride; In hexane; dichloromethane; at -78 ℃; for 0.333333h;

DOI:10.1039/b305623f

Reference yield: 79.0%

(E)-3-phenylpropenal (14371-10-9) + benzyltrimethylsilane (770-09-2) → (S)-3,4-diphenylbutanal (184483-51-0)

Guidance literature:

With 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate; C₂₉H₃₁F₁₄NOSi; trifluoroacetic acid; In acetonitrile; at -10 ℃; for 16h; enantioselective reaction; Irradiation; Sealed tube; Inert atmosphere;

DOI:10.1002/anie.202014876

upstream raw materials:

(S)-N-(tert-butoxycarbonyl)-N-(4-methoxyphenyl)-3,4-diphenyl-(Z)-1-buten-1-amine

(3'S,4S)-3-(3',4'-diphenylbutyryl)-4-phenyl-5,5-dimethyloxazolidin-2-one

Cinnamoyl chloride

benzylmagnesium chloride

Downstream raw materials:

acide (-)-3,4-diphenylbutanoique