S-(2-methyl-5-tert-butylphenyl)-2,6-di-O-benzyl-3-O-fluorenylmethoxycarbonyl-1-thio-β-D-glucopyranoside

Base Information

Chemical Name:S-(2-methyl-5-tert-butylphenyl)-2,6-di-O-benzyl-3-O-fluorenylmethoxycarbonyl-1-thio-β-D-glucopyranoside
CAS No.:1334540-47-4
Molecular Formula:C₄₆H₄₈O₇S
Molecular Weight:744.949
Hs Code.:

Synonyms:S-(2-methyl-5-tert-butylphenyl)-2,6-di-O-benzyl-3-O-fluorenylmethoxycarbonyl-1-thio-β-D-glucopyranoside

Suppliers and Price of S-(2-methyl-5-tert-butylphenyl)-2,6-di-O-benzyl-3-O-fluorenylmethoxycarbonyl-1-thio-β-D-glucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of S-(2-methyl-5-tert-butylphenyl)-2,6-di-O-benzyl-3-O-fluorenylmethoxycarbonyl-1-thio-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of S-(2-methyl-5-tert-butylphenyl)-2,6-di-O-benzyl-3-O-fluorenylmethoxycarbonyl-1-thio-β-D-glucopyranoside

There total 12 articles about S-(2-methyl-5-tert-butylphenyl)-2,6-di-O-benzyl-3-O-fluorenylmethoxycarbonyl-1-thio-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1334540-44-1
S-(2-methyl-5-tert-butylphenyl) 4,6-O-benzylidene-2-O-benzyl-3-O-fluorenylmethoxycarbonyl-1-thio-β-D-glucopyranoside

: 1334540-47-4
S-(2-methyl-5-tert-butylphenyl)-2,6-di-O-benzyl-3-O-fluorenylmethoxycarbonyl-1-thio-β-D-glucopyranoside

Guidance literature:: With trifluorormethanesulfonic acid; N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid; In dichloromethane; at -78 ℃; for 3h; regioselective reaction; Molecular sieve;
DOI:10.1039/c1cc13614c

Reference yield:

: 604-69-3
β-D-glucose pentaacetate

: 1334540-47-4
S-(2-methyl-5-tert-butylphenyl)-2,6-di-O-benzyl-3-O-fluorenylmethoxycarbonyl-1-thio-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 8 steps

1: boron trifluoride diethyl etherate / dichloromethane

2: sodium methylate / methanol / 20 °C

3: camphor-10-sulfonic acid / acetonitrile / 2.5 h / 20 °C / Inert atmosphere

4: 1H-imidazole / N,N-dimethyl-formamide / 4 h / 0 °C

5: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C

6: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C

7: pyridine / dichloromethane

8: trifluorormethanesulfonic acid; N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid / dichloromethane / 3 h / -78 °C / Molecular sieve

With pyridine; 1H-imidazole; trifluorormethanesulfonic acid; N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; sodium methylate; sodium hydride; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1039/c1cc13614c

Reference yield:

: 1334540-41-8
S-(2-methyl-5-tert-butylphenyl) 4,6-O-benzylidene-2-O-benzyl-1-thio-?-D-glucopyranoside

: 1334540-47-4
S-(2-methyl-5-tert-butylphenyl)-2,6-di-O-benzyl-3-O-fluorenylmethoxycarbonyl-1-thio-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane

2: trifluorormethanesulfonic acid; N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid / dichloromethane / 3 h / -78 °C / Molecular sieve

With pyridine; trifluorormethanesulfonic acid; N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid; In dichloromethane;
DOI:10.1039/c1cc13614c