CH₃OCC₅H₄C₆H₁₁O₂C₃NOBr

Base Information

• Chemical Name: CH₃OCC₅H₄C₆H₁₁O₂C₃NOBr
• CAS No.: 934001-86-2
• Molecular Formula: C₁₆H₁₈BrNO₄
• Molecular Weight: 368.227
• Mol file: 934001-86-2.mol

Synonyms:CH₃OCC₅H₄C₆H₁₁O₂C₃NOBr

Chemical Property of CH₃OCC₅H₄C₆H₁₁O₂C₃NOBr

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of CH₃OCC₅H₄C₆H₁₁O₂C₃NOBr

There total 1 articles about CH₃OCC₅H₄C₆H₁₁O₂C₃NOBr which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

1-bromo-2-(4-methoxyphenyl)acetylene (33675-41-1) + 2-(2-nitroethoxy)tetrahydro-2H-pyran (75233-61-3) → CH3OCC5H4C6H11O2C3NOBr (934001-86-2)

Guidance literature:

With phenyl isocyanate; N-ethyl-N,N-diisopropylamine; In toluene; at 90 ℃;

DOI:10.1016/j.tetlet.2007.01.040

Reference yield:

CH3OCC5H4C6H11O2C3NOBr (934001-86-2) → CH3OCC5H4C4H3O2NBr (934001-96-4)

Guidance literature:

With Dowex-H⁺ resin; In methanol; at 23 ℃;

DOI:10.1016/j.tetlet.2007.01.040

Reference yield:

CH3OCC5H4C6H11O2C3NOBr (934001-86-2) → CH3OCOC5H4C4HO2NBr

Guidance literature:

Multi-step reaction with 3 steps

1: Dowex-H⁺ resin / methanol / 23 °C

2: pyridine*SO₃; Et₃N / CH₂Cl₂; dimethylsulfoxide / 23 °C

3: NaClO₂; 2-methyl-2-butene; NaH₂PO₄ / 2-methyl-propan-2-ol; H₂O; tetrahydrofuran / 20 °C

With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; Dowex-H⁺ resin; sulfur trioxide pyridine complex; triethylamine; In tetrahydrofuran; methanol; dichloromethane; water; dimethyl sulfoxide; tert-butyl alcohol;

DOI:10.1016/j.tetlet.2007.01.040

upstream raw materials:

1-bromo-2-(4-methoxyphenyl)acetylene

2-(2-nitroethoxy)tetrahydro-2H-pyran

Downstream raw materials:

CH₃OCC₅H₄C₄H₃O₂NBr