(E)-1-(3-ethylpyrazin-2-yl)-3-(4-fluorophenyl)prop-2-en-1-one

Base Information

• Chemical Name: (E)-1-(3-ethylpyrazin-2-yl)-3-(4-fluorophenyl)prop-2-en-1-one
• CAS No.: 1433999-48-4
• Molecular Formula: C₁₅H₁₃FN₂O
• Molecular Weight: 256.279
• Mol file: 1433999-48-4.mol

Synonyms:(E)-1-(3-ethylpyrazin-2-yl)-3-(4-fluorophenyl)prop-2-en-1-one

Chemical Property of (E)-1-(3-ethylpyrazin-2-yl)-3-(4-fluorophenyl)prop-2-en-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1-(3-ethylpyrazin-2-yl)-3-(4-fluorophenyl)prop-2-en-1-one

There total 1 articles about (E)-1-(3-ethylpyrazin-2-yl)-3-(4-fluorophenyl)prop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-fluorobenzaldehyde (459-57-4) + 2-ethyl-3-acetyl pyrazine (32974-92-8) → (E)-1-(3-ethylpyrazin-2-yl)-3-(4-fluorophenyl)prop-2-en-1-one (1433999-48-4)

Guidance literature:

With potassium carbonate; In neat (no solvent); at 70 ℃; for 0.125h; under 15001.5 Torr; Microwave irradiation;

DOI:10.1039/c3nj00308f

Reference yield: 88.0%

(E)-1-(3-ethylpyrazin-2-yl)-3-(4-fluorophenyl)prop-2-en-1-one (1433999-48-4) + thiosemicarbazide (79-19-6) → 3-(3-ethylpyrazin-2-yl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide

Guidance literature:

With sodium acetate; acetic acid; In water; at 30 - 33 ℃; for 1.25h; Reagent/catalyst; Solvent; Sonication; UV-irradiation; Green chemistry;

DOI:10.1039/c4nj00594e

upstream raw materials:

4-fluorobenzaldehyde

2-ethyl-3-acetyl pyrazine