2-bromo-N-(2-bromoethyl)-N-(3,4-dichlorobenzyl)ethanamine

Base Information

• Chemical Name: 2-bromo-N-(2-bromoethyl)-N-(3,4-dichlorobenzyl)ethanamine
• CAS No.: 1096706-57-8
• Molecular Formula: C₁₁H₁₃Br₂Cl₂N
• Molecular Weight: 389.945
• Mol file: 1096706-57-8.mol

Synonyms:2-bromo-N-(2-bromoethyl)-N-(3,4-dichlorobenzyl)ethanamine

Chemical Property of 2-bromo-N-(2-bromoethyl)-N-(3,4-dichlorobenzyl)ethanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-bromo-N-(2-bromoethyl)-N-(3,4-dichlorobenzyl)ethanamine

There total 2 articles about 2-bromo-N-(2-bromoethyl)-N-(3,4-dichlorobenzyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[(2-Hydroxy-ethyl)-(3,4-dichloro-benzyl)-amino]-ethanol (60876-94-0) → 2-bromo-N-(2-bromoethyl)-N-(3,4-dichlorobenzyl)ethanamine (1096706-57-8)

Guidance literature:

With phosphorus tribromide; In chloroform; at 20 - 60 ℃;

DOI:10.1016/j.ejmech.2010.06.012

Reference yield:

3,4-Dichlorophenylmethyl chloride (102-47-6) → 2-bromo-N-(2-bromoethyl)-N-(3,4-dichlorobenzyl)ethanamine (1096706-57-8)

Guidance literature:

Multi-step reaction with 2 steps

1: acetonitrile / 50 °C

2: phosphorus tribromide / chloroform / 2 h / Reflux

With phosphorus tribromide; In chloroform; acetonitrile;

DOI:10.1016/j.bmcl.2012.12.036 DOI:10.1016/j.bmc.2013.05.007

Reference yield: 75.6%

1,2,4-Triazole (288-88-0) + 2-bromo-N-(2-bromoethyl)-N-(3,4-dichlorobenzyl)ethanamine (1096706-57-8) → N-(2-(1H-1,2,4-triazol-1-yl)ethyl)-N-(3,4-dichlorobenzyl)-2-(1H-1,2,4-triazol-1-yl)ethanamine (1096706-41-0)

Guidance literature:

1,2,4-Triazole; With potassium carbonate; In acetonitrile; at 60 ℃; for 1h;

2-bromo-N-(2-bromoethyl)-N-(3,4-dichlorobenzyl)ethanamine; In acetonitrile; at 20 - 60 ℃;

DOI:10.1016/j.ejmech.2010.06.012

upstream raw materials:

2-[(2-Hydroxy-ethyl)-(3,4-dichloro-benzyl)-amino]-ethanol

3,4-Dichlorophenylmethyl chloride

Downstream raw materials:

N-(2-(1H-imidazol-1-yl)ethyl)-N-(3,4-dichlorobenzyl)-2-(1H-imidazol-1-yl)ethanamine

N-(2-(1H-1,2,4-triazol-1-yl)ethyl)-N-(3,4-dichlorobenzyl)-2-(1H-1,2,4-triazol-1-yl)ethanamine

C₃₂H₃₀Cl₂N₅O₄⁽¹⁺⁾*Cl^(1-)

N-(2-(1,2,4-triazol-1-yl)ethyl)-2-bromo-N-(3,4-dichlorobenzyl)ethanamine