3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-carbaldehyde oxime

Base Information

• Chemical Name: 3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-carbaldehyde oxime
• CAS No.: 500692-83-1
• Molecular Formula: C₂₈H₃₁NO₆
• Molecular Weight: 477.557
• Mol file: 500692-83-1.mol

Synonyms:3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-carbaldehyde oxime

Chemical Property of 3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-carbaldehyde oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-carbaldehyde oxime

There total 1 articles about 3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-carbaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 6-aldehydo-2,3,4-tri-O-benzyl-α-D-glucopyranoside (83051-88-1) → 3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-carbaldehyde oxime (500692-83-1)

Guidance literature:

With sodium carbonate; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1016/j.tetlet.2007.09.007

Reference yield: 81.0%

2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-deoxy-β-D-manno-hept-1-enitol (97321-70-5,133697-34-4) + 3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-carbaldehyde oxime (500692-83-1) → C56H58N2O12 + methyl (5'R)-2,3,4-tri-O-benzyl-5-{(5R,7R,8R,9S,10S)-8,9,10-tris(benzyloxy)-7-[(benzyloxy)methyl]-1,6-dioxa-2-azaspiro[4.5]dec-2-en-3-yl}-α-D-xylopyranoside

Guidance literature:

3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-carbaldehyde oxime; With N-chloro-succinimide; In 1,2-dichloro-ethane; for 0.333333h; Heating;

2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-deoxy-β-D-manno-hept-1-enitol; With triethylamine; In 1,2-dichloro-ethane; for 24h; Further stages.; Heating;

DOI:10.1016/j.tetlet.2007.09.007

Reference yield: 65.0%

2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-deoxy-D-gluco-hept-1-enitol (133697-34-4,97321-70-5) + 3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-carbaldehyde oxime (500692-83-1) → methyl (5'R)-2,3,4-tri-O-benzyl-5-{(5R,7R,8R,9S,10R)-8,9,10-tris(benzyloxy)-7-[(benzyloxy)methyl]-1,6-dioxa-2-azaspiro[4.5]dec-2-en-3-yl}-α-D-xylopyranoside + C56H58N2O12

Guidance literature:

3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-carbaldehyde oxime; With N-chloro-succinimide; In 1,2-dichloro-ethane; for 0.333333h; Heating;

2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-deoxy-D-gluco-hept-1-enitol; With triethylamine; In 1,2-dichloro-ethane; for 24h; Further stages.; Heating;

DOI:10.1016/j.tetlet.2007.09.007

upstream raw materials:

methyl 6-aldehydo-2,3,4-tri-O-benzyl-α-D-glucopyranoside

Downstream raw materials:

C₆₅H₆₉NO₁₁

C₆₅H₆₉NO₁₁

C₆₅H₆₉NO₁₁

C₆₅H₆₉NO₁₁