2-[benzo(d)thiazol-2-ylcarbamoyl]phenyl 2,4,6-tri-O-acetyl-3-O-prop-2-ynyl-1-thio-β-D-galactopyranoside

Base Information

Chemical Name:2-[benzo(d)thiazol-2-ylcarbamoyl]phenyl 2,4,6-tri-O-acetyl-3-O-prop-2-ynyl-1-thio-β-D-galactopyranoside
CAS No.:1312289-94-3
Molecular Formula:C₂₉H₂₈N₂O₉S₂
Molecular Weight:612.681
Hs Code.:

Synonyms:2-[benzo(d)thiazol-2-ylcarbamoyl]phenyl 2,4,6-tri-O-acetyl-3-O-prop-2-ynyl-1-thio-β-D-galactopyranoside

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[benzo(d)thiazol-2-ylcarbamoyl]phenyl 2,4,6-tri-O-acetyl-3-O-prop-2-ynyl-1-thio-β-D-galactopyranoside

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-[benzo(d)thiazol-2-ylcarbamoyl]phenyl 2,4,6-tri-O-acetyl-3-O-prop-2-ynyl-1-thio-β-D-galactopyranoside

There total 6 articles about 2-[benzo(d)thiazol-2-ylcarbamoyl]phenyl 2,4,6-tri-O-acetyl-3-O-prop-2-ynyl-1-thio-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 136-95-8,102337-98-4,84293-42-5
2-amino-benzthiazole

: 1312289-93-2
C₂₂H₂₄O₁₀S

: 1312289-94-3
2-[benzo(d)thiazol-2-ylcarbamoyl]phenyl 2,4,6-tri-O-acetyl-3-O-prop-2-ynyl-1-thio-β-D-galactopyranoside

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 2.5h; Inert atmosphere;
DOI:10.1016/j.bmc.2011.03.022

Reference yield:

: 1312289-92-1
C₁₆H₁₈O₇S

: 1312289-94-3
2-[benzo(d)thiazol-2-ylcarbamoyl]phenyl 2,4,6-tri-O-acetyl-3-O-prop-2-ynyl-1-thio-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; dmap / 48 h / 20 °C / Inert atmosphere

2: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 2.5 h / 20 °C / Inert atmosphere

With pyridine; dmap; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2011.03.022

Reference yield:

: 25878-60-8
D-galactose pentaacetate

: 1312289-94-3
2-[benzo(d)thiazol-2-ylcarbamoyl]phenyl 2,4,6-tri-O-acetyl-3-O-prop-2-ynyl-1-thio-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1.1: boron trifluoride diethyl etherate / dichloromethane / 17 h / 20 °C / Inert atmosphere

2.1: methanol; sodium methylate / 20 °C / Inert atmosphere

3.1: di(n-butyl)tin oxide / methanol / 2 h / Reflux; Inert atmosphere

3.2: 22 h / Reflux; Inert atmosphere

4.1: lithium hydroxide / methanol; water / 0.75 h / Inert atmosphere

4.2: amberlite IR-120 / Inert atmosphere

5.1: pyridine; dmap / 48 h / 20 °C / Inert atmosphere

6.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 2.5 h / 20 °C / Inert atmosphere

With pyridine; methanol; dmap; boron trifluoride diethyl etherate; sodium methylate; di(n-butyl)tin oxide; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; lithium hydroxide; In methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2011.03.022