Ethyl 2-Mesitylenesulfonyloximino-3,3-bis(trifluoromethyl) Propionate

Base Information

• Chemical Name: Ethyl 2-Mesitylenesulfonyloximino-3,3-bis(trifluoromethyl) Propionate
• CAS No.: 92629-23-7
• Molecular Formula: C₁₆H₁₇F₆NO₅S
• Molecular Weight: 449.371
• Mol file: 92629-23-7.mol

Synonyms:Ethyl 2-Mesitylenesulfonyloximino-3,3-bis(trifluoromethyl) Propionate

Chemical Property of Ethyl 2-Mesitylenesulfonyloximino-3,3-bis(trifluoromethyl) Propionate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethyl 2-Mesitylenesulfonyloximino-3,3-bis(trifluoromethyl) Propionate

There total 3 articles about Ethyl 2-Mesitylenesulfonyloximino-3,3-bis(trifluoromethyl) Propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

2-mesitylenesulphonyl chloride (773-64-8) + Ethyl 2-Oximino-3,3-bis(trifluoromethyl) Propionate (92629-22-6) → Ethyl 2-Mesitylenesulfonyloximino-3,3-bis(trifluoromethyl) Propionate (92629-23-7)

Guidance literature:

With N,N'-dimethylbenzylamine; In diethyl ether; at 0 ℃; for 1h;

DOI:10.1007/BF00506963

Reference yield:

ethyl 4,4,4-trifluoro-3-(trifluoromethyl)crotonate (1513-60-6) → Ethyl 2-Mesitylenesulfonyloximino-3,3-bis(trifluoromethyl) Propionate (92629-23-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 72 percent / hydroxylamine / ethanol / 1 h / -20 °C

2: 60 percent / tert-butyl hypochlorite / ethyl acetate / 0.5 h / 0 °C

3: 45 percent / N,N-dimethylbenzylamine / diethyl ether / 1 h / 0 °C

With N,N'-dimethylbenzylamine; tert-butylhypochlorite; hydroxylamine; In diethyl ether; ethanol; ethyl acetate;

DOI:10.1007/BF00506963

Reference yield:

ethyl 4,4,4-trifluoro-2-(hydroxyamino)-3-(trifluoromethyl) butanoate (92629-48-6) → Ethyl 2-Mesitylenesulfonyloximino-3,3-bis(trifluoromethyl) Propionate (92629-23-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / tert-butyl hypochlorite / ethyl acetate / 0.5 h / 0 °C

2: 45 percent / N,N-dimethylbenzylamine / diethyl ether / 1 h / 0 °C

With N,N'-dimethylbenzylamine; tert-butylhypochlorite; In diethyl ether; ethyl acetate;

DOI:10.1007/BF00506963

upstream raw materials:

2-mesitylenesulphonyl chloride

Ethyl 2-Oximino-3,3-bis(trifluoromethyl) Propionate

ethyl 4,4,4-trifluoro-3-(trifluoromethyl)crotonate

ethyl 4,4,4-trifluoro-2-(hydroxyamino)-3-(trifluoromethyl) butanoate