Technology Process of C25H24FN3O5
There total 2 articles about C25H24FN3O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C25H28FN3O5;
With
2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
tetrahydrofuran;
at 85 ℃;
for 1h;
With
sodium hydrogencarbonate;
In
ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: chloro-trimethyl-silane / 20 h / 0 - 20 °C
2: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 16 h / 0 - 20 °C
3: 2,3-dicyano-5,6-dichloro-p-benzoquinone / tetrahydrofuran / 1 h / 85 °C
With
chloro-trimethyl-silane; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
tetrahydrofuran; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: hydrogen / palladium 10% on activated carbon / methanol / 1 h
2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 16 h / 0 - 20 °C
3.1: potassium carbonate; N,N,N,N-tetraethylammonium tetrafluoroborate / N,N-dimethyl-formamide; water / 72 h / Electrochemical reaction
4.1: water; lithium hydroxide / methanol / 18 h / 20 °C / Cooling with ice
4.2: 10 °C
5.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 16 h / 0 - 20 °C
6.1: (bis-(2-methoxyethyl)amino)sulfur trufluoride / dichloromethane / -20 - 20 °C
With
water; hydrogen; N,N,N,N-tetraethylammonium tetrafluoroborate; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; lithium hydroxide; (bis-(2-methoxyethyl)amino)sulfur trufluoride;
palladium 10% on activated carbon;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide;