28-O-2,3,4-tri-O-benzoyl-α-L-arabinopyranosylbetulin 3β-O-2',3',4'-tri-O-benzoyl-α-L-rhamnopyranoside

Base Information

• Chemical Name: 28-O-2,3,4-tri-O-benzoyl-α-L-arabinopyranosylbetulin 3β-O-2',3',4'-tri-O-benzoyl-α-L-rhamnopyranoside
• CAS No.: 1334393-26-8
• Molecular Formula: C₈₃H₉₂O₁₆
• Molecular Weight: 1345.63
• Mol file: 1334393-26-8.mol

Synonyms:28-O-2,3,4-tri-O-benzoyl-α-L-arabinopyranosylbetulin 3β-O-2',3',4'-tri-O-benzoyl-α-L-rhamnopyranoside

Chemical Property of 28-O-2,3,4-tri-O-benzoyl-α-L-arabinopyranosylbetulin 3β-O-2',3',4'-tri-O-benzoyl-α-L-rhamnopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 28-O-2,3,4-tri-O-benzoyl-α-L-arabinopyranosylbetulin 3β-O-2',3',4'-tri-O-benzoyl-α-L-rhamnopyranoside

There total 3 articles about 28-O-2,3,4-tri-O-benzoyl-α-L-arabinopyranosylbetulin 3β-O-2',3',4'-tri-O-benzoyl-α-L-rhamnopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

betulin 3β-O-2,3,4-tri-O-benzoyl-α-L-rhamnopyranoside (1104398-66-4) + 2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl ortho-hex-1-ynylbenzoate → 28-O-2,3,4-tri-O-benzoyl-α-L-arabinopyranosylbetulin 3β-O-2',3',4'-tri-O-benzoyl-α-L-rhamnopyranoside (1334393-26-8)

Guidance literature:

betulin 3β-O-2,3,4-tri-O-benzoyl-α-L-rhamnopyranoside; 2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl ortho-hex-1-ynylbenzoate; In dichloromethane; at 20 ℃; for 0.5h; Molecular sieve;

With [bis(trifluoromethanesulfonyl)imidate](triphenylphosphine)gold(I); In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1021/ol202232v

Reference yield: 87.0%

28-O-(2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl) betulin + 2,3,4-tri-O-benzoyl-α/β-L- rhamnopyranoside trichloroacetimidate (206257-92-3) → 3β-O-(2,3,4-tri-O-benzoyl-α-L-rhamnopyranosyl) allolbetulin + 28-O-2,3,4-tri-O-benzoyl-α-L-arabinopyranosylbetulin 3β-O-2',3',4'-tri-O-benzoyl-α-L-rhamnopyranoside (1334393-26-8)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -40 ℃; for 0.0666667h; Flow reactor;

DOI:10.1016/j.carres.2018.03.006

Reference yield: 57.0%

28-O-(2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl) betulin + 2,3,4-tri-O-benzoyl-α/β-L- rhamnopyranoside trichloroacetimidate (206257-92-3) → 28-O-2,3,4-tri-O-benzoyl-α-L-arabinopyranosylbetulin 3β-O-2',3',4'-tri-O-benzoyl-α-L-rhamnopyranoside (1334393-26-8)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -40 ℃; for 0.0666667h; Flow reactor;

DOI:10.1016/j.carres.2018.03.006

upstream raw materials:

betulin 3β-O-2,3,4-tri-O-benzoyl-α-L-rhamnopyranoside

2,3,4-tri-O-benzoyl-α/β-L- rhamnopyranoside trichloroacetimidate