3-[(4-Nitro-phenyl)-hydrazono]-3,4-dihydro-1H-quinoxalin-2-one

Base Information

• Chemical Name: 3-[(4-Nitro-phenyl)-hydrazono]-3,4-dihydro-1H-quinoxalin-2-one
• CAS No.: 204512-15-2
• Molecular Formula: C₁₄H₁₁N₅O₃
• Molecular Weight: 297.273
• Mol file: 204512-15-2.mol

Synonyms:3-[(4-Nitro-phenyl)-hydrazono]-3,4-dihydro-1H-quinoxalin-2-one

Chemical Property of 3-[(4-Nitro-phenyl)-hydrazono]-3,4-dihydro-1H-quinoxalin-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[(4-Nitro-phenyl)-hydrazono]-3,4-dihydro-1H-quinoxalin-2-one

There total 1 articles about 3-[(4-Nitro-phenyl)-hydrazono]-3,4-dihydro-1H-quinoxalin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

chloro-(4-nitro-phenylhydrazono)-acetic acid ethyl ester (27143-13-1) + 1,2-diamino-benzene (95-54-5) → 3-[(4-Nitro-phenyl)-hydrazono]-3,4-dihydro-1H-quinoxalin-2-one (204512-15-2)

Guidance literature:

With triethylamine; In ethanol; for 3h; Heating;

DOI:10.1002/ardp.19973301206

Reference yield: 92.0%

bis(trichloromethyl) carbonate (32315-10-9) + 3-[(4-Nitro-phenyl)-hydrazono]-3,4-dihydro-1H-quinoxalin-2-one (204512-15-2) → 2-(4-Nitro-phenyl)-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione (204511-89-7)

Guidance literature:

In tetrahydrofuran; for 5h; Heating;

DOI:10.1002/ardp.19973301206

Reference yield:

3-[(4-Nitro-phenyl)-hydrazono]-3,4-dihydro-1H-quinoxalin-2-one (204512-15-2) → 2-(4-Amino-phenyl)-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione (204511-91-1)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / Heating

2: H₂ / Pd/C / dimethylformamide

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1021/jm031136l

upstream raw materials:

chloro-(4-nitro-phenylhydrazono)-acetic acid ethyl ester

1,2-diamino-benzene

Downstream raw materials:

2-(4-Nitro-phenyl)-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione

2-(4-Amino-phenyl)-2H,5H-[1,2,4]triazolo[4,3-a]quinoxaline-1,4-dione

4-chloro-2-(4-nitro-phenyl)-2H-[1,2,4]triazolo[4,3-a]quinoxalin-1-one

4-amino-2-(4-nitrophenyl)-1,2,4-triazolo[4,3-a]quinoxalin-1-one