1-amino-2-(3-phenoxyprop-1-ynyl)-4-(p-toluidino)-9,10-anthraquinone

Base Information

• Chemical Name: 1-amino-2-(3-phenoxyprop-1-ynyl)-4-(p-toluidino)-9,10-anthraquinone
• CAS No.: 1450664-40-0
• Molecular Formula: C₃₀H₂₂N₂O₃
• Molecular Weight: 458.516
• Mol file: 1450664-40-0.mol

Synonyms:1-amino-2-(3-phenoxyprop-1-ynyl)-4-(p-toluidino)-9,10-anthraquinone

Chemical Property of 1-amino-2-(3-phenoxyprop-1-ynyl)-4-(p-toluidino)-9,10-anthraquinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-amino-2-(3-phenoxyprop-1-ynyl)-4-(p-toluidino)-9,10-anthraquinone

There total 1 articles about 1-amino-2-(3-phenoxyprop-1-ynyl)-4-(p-toluidino)-9,10-anthraquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

1-phenoxy-2-propyne (13610-02-1) + 1-amino-2-bromo-4-(p-toluidino)-9,10-anthraquinone (128-83-6) → 1-amino-2-(3-phenoxyprop-1-ynyl)-4-(p-toluidino)-9,10-anthraquinone (1450664-40-0)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In toluene; at 55 ℃; for 3.5h; Inert atmosphere;

DOI:10.1007/s11172-012-0292-2

Reference yield: 60.0%

1-amino-2-(3-phenoxyprop-1-ynyl)-4-(p-toluidino)-9,10-anthraquinone (1450664-40-0) → 1-azido-2-(3-phenoxyprop-1-ynyl)-4-(p-toluidino)-9,10-anthraquinone (1450664-44-4)

Guidance literature:

1-amino-2-(3-phenoxyprop-1-ynyl)-4-(p-toluidino)-9,10-anthraquinone; With i-propyl nitrite; In acetic acid; at 25 ℃; for 0.916667h;

With sodium azide; In water; acetic acid; at 25 ℃; for 2h;

DOI:10.1007/s11172-012-0292-2

Reference yield:

1-amino-2-(3-phenoxyprop-1-ynyl)-4-(p-toluidino)-9,10-anthraquinone (1450664-40-0) → 3-(3-phenoxyprop-1-ynyl)-5-(p-toluidino)-6H-anthra[1,9-c,d]isoxazol-6-one (1450664-48-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: i-propyl nitrite / acetic acid / 0.92 h / 25 °C

1.2: 2 h / 25 °C

2.1: toluene / 0.08 h / 110 °C

With i-propyl nitrite; In acetic acid; toluene;

DOI:10.1007/s11172-012-0292-2

upstream raw materials:

1-phenoxy-2-propyne

1-amino-2-bromo-4-(p-toluidino)-9,10-anthraquinone

Downstream raw materials:

1-azido-2-(3-phenoxyprop-1-ynyl)-4-(p-toluidino)-9,10-anthraquinone

3-(3-phenoxyprop-1-ynyl)-5-(p-toluidino)-6H-anthra[1,9-c,d]isoxazol-6-one