4-(ethyloxy)-N₂-{1-[trans-1-methyl-4-(ethyloxy)cyclohexyl]-4-piperidinyl}-1,2-benzenediamine

Base Information

• Chemical Name: 4-(ethyloxy)-N₂-{1-[trans-1-methyl-4-(ethyloxy)cyclohexyl]-4-piperidinyl}-1,2-benzenediamine
• CAS No.: 950773-13-4
• Molecular Formula: C₂₂H₃₇N₃O₂
• Molecular Weight: 375.555

Synonyms:4-(ethyloxy)-N₂-{1-[trans-1-methyl-4-(ethyloxy)cyclohexyl]-4-piperidinyl}-1,2-benzenediamine

Chemical Property of 4-(ethyloxy)-N₂-{1-[trans-1-methyl-4-(ethyloxy)cyclohexyl]-4-piperidinyl}-1,2-benzenediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(ethyloxy)-N₂-{1-[trans-1-methyl-4-(ethyloxy)cyclohexyl]-4-piperidinyl}-1,2-benzenediamine

There total 12 articles about 4-(ethyloxy)-N₂-{1-[trans-1-methyl-4-(ethyloxy)cyclohexyl]-4-piperidinyl}-1,2-benzenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-[5-(ethyloxy)-2-nitrophenyl]-1-[trans-1-methyl-4-(ethyloxy)cyclohexyl]-4-piperidinamine (950773-12-3) → 4-(ethyloxy)-N2-{1-[trans-1-methyl-4-(ethyloxy)cyclohexyl]-4-piperidinyl}-1,2-benzenediamine (950773-13-4)

Guidance literature:

With hydrazine; nickel; In ethanol; at 40 ℃; for 0.5h;

Reference yield:

N-ethyl-4-piperidone (3612-18-8) → 4-(ethyloxy)-N2-{1-[trans-1-methyl-4-(ethyloxy)cyclohexyl]-4-piperidinyl}-1,2-benzenediamine (950773-13-4)

Guidance literature:

Multi-step reaction with 6 steps

1: acetone / 3 h / 0 - 30 °C

2: potassium carbonate / ethanol; water / 2 h / 20 - 80 °C

3: ammonia; hydrogen / palladium 10% on activated carbon / methanol / 20 °C / 2585.81 Torr

4: hydrogenchloride / methanol; diethyl ether / 0.17 h

5: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.33 h / 200 °C / Microwave reactor

6: hydrazine / nickel / ethanol / 0.5 h / 40 °C

With hydrogenchloride; ammonia; hydrogen; potassium carbonate; N-ethyl-N,N-diisopropylamine; hydrazine; palladium 10% on activated carbon; nickel; In methanol; diethyl ether; ethanol; water; N,N-dimethyl-formamide; acetone;

Reference yield:

cis/trans-4-(ethyloxy)-1-methylcyclohexanecarboxylic acid (950772-11-9) → 4-(ethyloxy)-N2-{1-[trans-1-methyl-4-(ethyloxy)cyclohexyl]-4-piperidinyl}-1,2-benzenediamine (950773-13-4)

Guidance literature:

Multi-step reaction with 8 steps

1.1: thionyl chloride / toluene / 4 h / 20 - 85 °C

1.2: 0.33 h / 20 °C

2.1: diphenyl phosphoryl azide; triethylamine / toluene / 1 h / 20 - 85 °C

3.1: hydrogenchloride / tetrahydrofuran; water / 20 °C

4.1: potassium carbonate / ethanol; water / 2 h / 20 - 80 °C

5.1: ammonia; hydrogen / palladium 10% on activated carbon / methanol / 20 °C / 2585.81 Torr

6.1: hydrogenchloride / methanol; diethyl ether / 0.17 h

7.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.33 h / 200 °C / Microwave reactor

8.1: hydrazine / nickel / ethanol / 0.5 h / 40 °C

With hydrogenchloride; thionyl chloride; diphenyl phosphoryl azide; ammonia; hydrogen; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; hydrazine; palladium 10% on activated carbon; nickel; In tetrahydrofuran; methanol; diethyl ether; ethanol; water; N,N-dimethyl-formamide; toluene;

upstream raw materials:

N-[5-(ethyloxy)-2-nitrophenyl]-1-[trans-1-methyl-4-(ethyloxy)cyclohexyl]-4-piperidinamine

N-ethyl-4-piperidone

cis/trans-4-(ethyloxy)-1-methylcyclohexanecarboxylic acid

trans-4-(ethyloxy)-1-isocyanato-1-methylcyclohexane

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 950773-13-4 4-(ethyloxy)-N₂-{1-[trans-1-methyl-4-(ethyloxy)cyclohexyl]-4-piperidinyl}-1,2-benzenediamine

Send

Send

Metric Ton KG G Pound L ML

Send

Send