1α,6α-di-(4-methoxy-benzyloxy)-10-epi-eudesm-4(5)-en-3-one

Base Information

Chemical Name:1α,6α-di-(4-methoxy-benzyloxy)-10-epi-eudesm-4(5)-en-3-one
CAS No.:741259-16-5
Molecular Formula:C₃₁H₄₀O₅
Molecular Weight:492.656
Hs Code.:

Synonyms:1α,6α-di-(4-methoxy-benzyloxy)-10-epi-eudesm-4(5)-en-3-one

Suppliers and Price of 1α,6α-di-(4-methoxy-benzyloxy)-10-epi-eudesm-4(5)-en-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1α,6α-di-(4-methoxy-benzyloxy)-10-epi-eudesm-4(5)-en-3-one

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1α,6α-di-(4-methoxy-benzyloxy)-10-epi-eudesm-4(5)-en-3-one

There total 9 articles about 1α,6α-di-(4-methoxy-benzyloxy)-10-epi-eudesm-4(5)-en-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6485-40-1,2244-16-8
(R)-Carvone

: 741259-16-5
1α,6α-di-(4-methoxy-benzyloxy)-10-epi-eudesm-4(5)-en-3-one

Guidance literature:: Multi-step reaction with 11 steps

1.1: H₂ / Pd/C / ethanol / 30 h

1.2: 90 percent / NEt₃ / dimethylformamide / 48 h / Heating

2.1: 670 mg / TiCl₄ / CH₂Cl₂ / -78 - -40 °C

3.1: 85 percent / p-TsOH / CH₂Cl₂ / 24 h / 20 °C

4.1: NaOH / methanol / 3 h / 0 °C

5.1: 1.06 g / PCC; pyridine; SiO₂ / CH₂Cl₂ / 20 °C

6.1: tetrahydrofuran / 0.5 h / -78 °C

7.1: 880 mg / PCC; pyridine; SiO₂ / CH₂Cl₂ / 48 h / 20 °C

8.1: NaOMe / methanol / 2 h / 20 °C

8.2: 87 percent / MsCl; NEt₃ / CH₂Cl₂ / 8 h / 20 °C

9.1: 82 percent / NaOAc; DMAP / 0.33 h / Heating

10.1: 83 percent / m-CPBA / CH₂Cl₂ / 24 h / 20 °C

11.1: 82 percent / p-TsOH / CH₂Cl₂ / 24 h / 20 °C

With pyridine; dmap; sodium hydroxide; hydrogen; sodium methylate; sodium acetate; silica gel; titanium tetrachloride; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; dichloromethane; 2.1: Mukaiyama aldol reaction;
DOI:10.1016/j.tet.2004.05.056

Reference yield:

: 89238-99-3
O-(4-methoxybenzyl)-trichloroacetimidate

: 741259-16-5
1α,6α-di-(4-methoxy-benzyloxy)-10-epi-eudesm-4(5)-en-3-one

Guidance literature:: Multi-step reaction with 9 steps

1.1: 85 percent / p-TsOH / CH₂Cl₂ / 24 h / 20 °C

2.1: NaOH / methanol / 3 h / 0 °C

3.1: 1.06 g / PCC; pyridine; SiO₂ / CH₂Cl₂ / 20 °C

4.1: tetrahydrofuran / 0.5 h / -78 °C

5.1: 880 mg / PCC; pyridine; SiO₂ / CH₂Cl₂ / 48 h / 20 °C

6.1: NaOMe / methanol / 2 h / 20 °C

6.2: 87 percent / MsCl; NEt₃ / CH₂Cl₂ / 8 h / 20 °C

7.1: 82 percent / NaOAc; DMAP / 0.33 h / Heating

8.1: 83 percent / m-CPBA / CH₂Cl₂ / 24 h / 20 °C

9.1: 82 percent / p-TsOH / CH₂Cl₂ / 24 h / 20 °C

With pyridine; dmap; sodium hydroxide; sodium methylate; sodium acetate; silica gel; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1016/j.tet.2004.05.056

Reference yield:

: 741259-10-9
3-(4β-isopropyl-1α-methyl-2-oxo-cyclohexyl)-3α-(4-methoxy-benzyloxy)-propionaldehyde

: 741259-16-5
1α,6α-di-(4-methoxy-benzyloxy)-10-epi-eudesm-4(5)-en-3-one

Guidance literature:: Multi-step reaction with 6 steps

1.1: tetrahydrofuran / 0.5 h / -78 °C

2.1: 880 mg / PCC; pyridine; SiO₂ / CH₂Cl₂ / 48 h / 20 °C

3.1: NaOMe / methanol / 2 h / 20 °C

3.2: 87 percent / MsCl; NEt₃ / CH₂Cl₂ / 8 h / 20 °C

4.1: 82 percent / NaOAc; DMAP / 0.33 h / Heating

5.1: 83 percent / m-CPBA / CH₂Cl₂ / 24 h / 20 °C

6.1: 82 percent / p-TsOH / CH₂Cl₂ / 24 h / 20 °C

With pyridine; dmap; sodium methylate; sodium acetate; silica gel; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1016/j.tet.2004.05.056