Amfonelic acid

Base Information

• Chemical Name: Amfonelic acid
• CAS No.: 15180-02-6
• Molecular Formula: C18H16N2O3
• Molecular Weight: 308.33
• Hs Code.: 2933990090
• European Community (EC) Number: 878-363-7
• UNII: RR302AR19Y
• DSSTox Substance ID: DTXSID40164877
• Nikkaji Number: J8.533B
• Wikipedia: Amfonelic_acid
• Wikidata: Q4745982
• NCI Thesaurus Code: C90833
• ChEMBL ID: CHEMBL35337
• Mol file: 15180-02-6.mol

Synonyms:7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid;amfonelic acid

Chemical Property of Amfonelic acid

Chemical Property:

• Appearance/Colour: yellow powder
• Vapor Pressure: 8.66E-11mmHg at 25°C
• Melting Point: >1000 °C
• Refractive Index: 1.63
• Boiling Point: 499.308 °C at 760 mmHg
• PKA: 3.50±0.20(Predicted)
• Flash Point: 255.772 °C
• PSA: 72.19000
• Density: 1.298 g/cm³
• LogP: 2.70540
• Solubility.: 0.1 M NaOH: soluble
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 308.11609238
• Heavy Atom Count: 23
• Complexity: 497

Purity/Quality:

Amfonelic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 40-43
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCN1C=C(C(=O)C2=C1N=C(C=C2)CC3=CC=CC=C3)C(=O)O
• Description: Amfonelic acid (AFA) is a dopamine reuptake inhibitor. Experiments on rats have shown that AFA treatment completely prevented the effects of methamphetamine on the dopaminergic system, both morphologically and biochemically.
• Uses: Stimulant (central).