methyl 3-{[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoate hydrochloride

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Chemical Name:methyl 3-{[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoate hydrochloride
CAS No.:1072001-75-2
Molecular Formula:C₂₃H₁₈ClFN₂O₄*ClH
Molecular Weight:477.319
Hs Code.:

Synonyms:methyl 3-{[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoate hydrochloride

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Chemical Property of methyl 3-{[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoate hydrochloride

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Technology Process of methyl 3-{[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoate hydrochloride

There total 1 articles about methyl 3-{[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 1072002-62-0
[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methanol

: 19438-10-9
methyl 3-hydroxybenzoate

: 1072001-75-2
methyl 3-{[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoate hydrochloride

Guidance literature:: [6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methanol; methyl 3-hydroxybenzoate; With tributylphosphine; 1,1'-azodicarbonyl-dipiperidine; In toluene; for 10h;

With hydrogenchloride; In 1,4-dioxane; for 2h;

Reference yield: 72.0%

: 1072001-75-2
methyl 3-{[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoate hydrochloride

: 1072001-76-3
3-{[6-(4-Chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoic acid hydrochloride

Guidance literature:: methyl 3-{[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoate hydrochloride; With water; sodium hydroxide; In 1,4-dioxane; at 60 ℃; for 2h;

With hydrogenchloride; In 1,4-dioxane; water;