Technology Process of (S)-1-(2-bromophenyl)prop-2-yn-1-ol
There total 5 articles about (S)-1-(2-bromophenyl)prop-2-yn-1-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
glucose dehydrogenase; D-glucose; alcohol dehydrogenases from Ralstonia species; NADPH;
In
dimethyl sulfoxide;
at 30 ℃;
for 24h;
pH=7.4;
stereoselective reaction;
Enzymatic reaction;
DOI:10.1002/cctc.201901543
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen; laccase from Trametes versicolor / tert-butyl methyl ether / 16 h / 30 °C / pH 5 / Enzymatic reaction
2: glucose dehydrogenase; D-glucose; NADPH; alcohol dehydrogenases from Ralstonia species / dimethyl sulfoxide / 24 h / 30 °C / pH 7.4 / Enzymatic reaction
With
glucose dehydrogenase; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; D-glucose; laccase from Trametes versicolor; alcohol dehydrogenases from Ralstonia species; oxygen; NADPH;
In
tert-butyl methyl ether; dimethyl sulfoxide;
DOI:10.1002/cctc.201901543
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tetrahydrofuran / 4 h / 0 °C / Inert atmosphere
2: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen; laccase from Trametes versicolor / tert-butyl methyl ether / 16 h / 30 °C / pH 5 / Enzymatic reaction
3: glucose dehydrogenase; D-glucose; NADPH; alcohol dehydrogenases from Ralstonia species / dimethyl sulfoxide / 24 h / 30 °C / pH 7.4 / Enzymatic reaction
With
glucose dehydrogenase; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; D-glucose; laccase from Trametes versicolor; alcohol dehydrogenases from Ralstonia species; oxygen; NADPH;
In
tetrahydrofuran; tert-butyl methyl ether; dimethyl sulfoxide;
DOI:10.1002/cctc.201901543
