4-nitrobenzylamine

Base Information

• Chemical Name: 4-nitrobenzylamine
• CAS No.: 7409-30-5
• Molecular Formula: C7H8 N2 O2
• Molecular Weight: 152.153
• Hs Code.: 2921499090
• Mol file: 7409-30-5.mol

Synonyms:Benzylamine,p-nitro- (6CI,7CI,8CI); (4-Nitrophenylmethyl)amine; 4-Nitrobenzenemethanamine;4-Nitrobenzylamine; p-Nitrobenzylamine

Chemical Property of 4-nitrobenzylamine

Chemical Property:

• Melting Point: 117-119℃
• Boiling Point: 298℃
• PKA: 8.36±0.10(Predicted)
• Flash Point: 134℃
• PSA: 71.84000
• Density: 1.254
• LogP: 2.27700
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

99% ^*data from raw suppliers

1-((4-Nitrophenyl))methanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-nitrobenzylamine

There total 48 articles about 4-nitrobenzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(4-nitrobenzyl)-1H-isoindole-1,3(2H)-dione (62133-07-7) → p-nitrobenzylamine (7409-30-5)

Guidance literature:

With methylamine; In ethanol; at 25 ℃; for 20h;

DOI:10.1002/hlca.200790105

Reference yield: 98.0%

4-nitrobenzonitrile (619-72-7) → p-nitrobenzylamine (7409-30-5)

Guidance literature:

With diisobutylaluminum borohydride; In tetrahydrofuran; at 25 ℃; for 1h; Inert atmosphere;

DOI:10.1021/acs.joc.0c03062

Reference yield: 93.0%

4-nitrobenzaldehyde oxime (1129-37-9,174848-02-3,20707-69-1) → p-nitrobenzylamine (7409-30-5)

Guidance literature:

With sodium hydrogensulfate monohydrate; molybdenum(V) chloride; sodium cyanoborohydride; In N,N-dimethyl-formamide; for 1.7h; Reflux;

DOI:10.5012/bkcs.2011.32.9.3323

upstream raw materials:

hexamethylenetetramine

4-nitrobenzyl chloride

1-bromomethyl-4-nitro-benzene

2-(4-nitrobenzyl)-1H-isoindole-1,3(2H)-dione

Downstream raw materials:

N,N′-bis(4-nitrobenzyl)urea

dichloro-acetic acid-(4-nitro-benzylamide)

1,6,7,1',6',7'-hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2']binaphthyl-8,8'-dicarbaldehyde bis-(4-nitro-benzylimine)

N,N'-bis-(4-nitro-benzyl)-thiourea