5-Chloro-3,trans-5-bis(carbomethoxy)-trans-2,cis-6-diphenyl-5,6-dihydro-4-hydroxy-2H-thiopyran

Base Information

Chemical Name:5-Chloro-3,trans-5-bis(carbomethoxy)-trans-2,cis-6-diphenyl-5,6-dihydro-4-hydroxy-2H-thiopyran
CAS No.:77461-80-4
Molecular Formula:C₂₁H₁₉ClO₅S
Molecular Weight:418.898
Hs Code.:

Synonyms:5-Chloro-3,trans-5-bis(carbomethoxy)-trans-2,cis-6-diphenyl-5,6-dihydro-4-hydroxy-2H-thiopyran

Suppliers and Price of 5-Chloro-3,trans-5-bis(carbomethoxy)-trans-2,cis-6-diphenyl-5,6-dihydro-4-hydroxy-2H-thiopyran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-Chloro-3,trans-5-bis(carbomethoxy)-trans-2,cis-6-diphenyl-5,6-dihydro-4-hydroxy-2H-thiopyran

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-Chloro-3,trans-5-bis(carbomethoxy)-trans-2,cis-6-diphenyl-5,6-dihydro-4-hydroxy-2H-thiopyran

There total 5 articles about 5-Chloro-3,trans-5-bis(carbomethoxy)-trans-2,cis-6-diphenyl-5,6-dihydro-4-hydroxy-2H-thiopyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 77461-76-8
3,5-Bis(carbomethoxy)-cis-2,trans-6-diphenyl-5,6-dihydro-4-hydroxy-2H-thiopyran

: 77461-80-4
5-Chloro-3,trans-5-bis(carbomethoxy)-trans-2,cis-6-diphenyl-5,6-dihydro-4-hydroxy-2H-thiopyran

Guidance literature:: With pyridine; N-chloro-succinimide; In dichloromethane; Ambient temperature;
DOI:10.1021/jo00326a030

Reference yield:

: 1830-54-2
3-oxopentanedioic acid dimethyl ester

: 77461-80-4
5-Chloro-3,trans-5-bis(carbomethoxy)-trans-2,cis-6-diphenyl-5,6-dihydro-4-hydroxy-2H-thiopyran

Guidance literature:: Multi-step reaction with 3 steps

1: 28 percent / ammonium acetate / toluene / 0.5 h / Heating

2: hydrogen sulfide (gas), sodium acetate / 1.) methanol, reflux, 6 h, 2.) room temp., overnight

3: 52 percent / N-chlorosuccinimide NCS, pyridine / CH₂Cl₂ / Ambient temperature

With pyridine; ammonium acetate; N-chloro-succinimide; hydrogen sulfide; sodium acetate; In dichloromethane; toluene;
DOI:10.1021/jo00326a030

Reference yield:

: 77461-75-7
Dimethyl Dibenzalacetonedicarboxylate

: 77461-80-4
5-Chloro-3,trans-5-bis(carbomethoxy)-trans-2,cis-6-diphenyl-5,6-dihydro-4-hydroxy-2H-thiopyran

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen sulfide (gas), sodium acetate / 1.) methanol, reflux, 6 h, 2.) room temp., overnight

2: 52 percent / N-chlorosuccinimide NCS, pyridine / CH₂Cl₂ / Ambient temperature

With pyridine; N-chloro-succinimide; hydrogen sulfide; sodium acetate; In dichloromethane;
DOI:10.1021/jo00326a030