β-valienol

Base Information

• Chemical Name: β-valienol
• CAS No.: 1325585-41-8
• Molecular Formula: C₇H₁₂O₅
• Molecular Weight: 176.169
• Mol file: 1325585-41-8.mol

Synonyms:β-valienol

Chemical Property of β-valienol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of β-valienol

There total 11 articles about β-valienol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

C19H36O9 (1323271-67-5) → β-valienol (1325585-41-8)

Guidance literature:

With trifluoroacetic acid; In water; at 20 ℃; for 0.5h;

DOI:10.1055/s-0030-1260547

Reference yield:

methyl (3R,4S,5S,6R)-3,4,5,6-tetraacetoxy-1-cyclohexenecarboxylate (1257516-75-8) → β-valienol (1325585-41-8)

Guidance literature:

With diisobutylaluminium hydride; In tetrahydrofuran; at 20 ℃; for 10h;

DOI:10.1016/j.molcatb.2010.07.009

Reference yield:

C21H43O13P → β-valienol (1325585-41-8)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium tetrahydroborate / methanol / 0.5 h / 20 °C

2.1: dimethyl sulfoxide; trifluoroacetic anhydride / dichloromethane / 5 h / -78 °C / Molecular sieve; Inert atmosphere

2.2: -78 - 20 °C / Inert atmosphere

3.1: cerium(III) chloride heptahydrate / methanol / 1 h / -20 °C

3.2: -20 °C

4.1: trifluoroacetic acid / water / 0.5 h / 20 °C

With sodium tetrahydroborate; cerium(III) chloride heptahydrate; dimethyl sulfoxide; trifluoroacetic acid; trifluoroacetic anhydride; In methanol; dichloromethane; water;

DOI:10.1055/s-0030-1260547

upstream raw materials:

methyl (3R,4S,5S,6R)-3,4,5,6-tetraacetoxy-1-cyclohexenecarboxylate

C₁₉H₃₄O₉

C₁₉H₃₆O₉

C₁₈H₃₄O₁₀

Downstream raw materials:

(1R,2S,3S,4R)-tetrahydroxy-5-acetoxymethylcyclohex-5-ene

(2S,3S,4R)-trihydroxy-5-hydroxymethylcyclohex-5-en-1-one