cyclopropanecarboxylic acid [4-(5-amino-1H-benzoimidazol-2-yl)-phenyl]-amide

Base Information

Chemical Name:cyclopropanecarboxylic acid [4-(5-amino-1H-benzoimidazol-2-yl)-phenyl]-amide
CAS No.:1026618-62-1
Molecular Formula:C₁₇H₁₆N₄O
Molecular Weight:292.34
Hs Code.:

cyclopropanecarboxylic acid [4-(5-amino-1<i>H</i>-benzoimidazol-2-yl)-phenyl]-amide

Synonyms:cyclopropanecarboxylic acid [4-(5-amino-1H-benzoimidazol-2-yl)-phenyl]-amide

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Chemical Property of cyclopropanecarboxylic acid [4-(5-amino-1H-benzoimidazol-2-yl)-phenyl]-amide

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Technology Process of cyclopropanecarboxylic acid [4-(5-amino-1H-benzoimidazol-2-yl)-phenyl]-amide

There total 4 articles about cyclopropanecarboxylic acid [4-(5-amino-1H-benzoimidazol-2-yl)-phenyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1026280-35-2
cyclopropanecarboxylic acid [4-(5-nitro-1H-benzoimidazol-2-yl)-phenyl]-amide

: 1026618-62-1
cyclopropanecarboxylic acid [4-(5-amino-1H-benzoimidazol-2-yl)-phenyl]-amide

Guidance literature:: With hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; at 80 ℃; for 16h;
DOI:10.1016/j.ejmech.2006.03.014

Reference yield:

: 150-13-0,159246-81-8,8014-65-1
4-amino-benzoic acid

: 1026618-62-1
cyclopropanecarboxylic acid [4-(5-amino-1H-benzoimidazol-2-yl)-phenyl]-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 47 percent / polyphosphoric acid / xylene / 60 - 150 °C

2: pyridine / 3 h / 20 °C

3: H₂ / Pd/C / methanol; tetrahydrofuran / 16 h / 80 °C

With pyridine; PPA; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; xylene;
DOI:10.1016/j.ejmech.2006.03.014

Reference yield:

: 99-56-9
4-Nitrophenylene-1,2-diamine

: 1026618-62-1
cyclopropanecarboxylic acid [4-(5-amino-1H-benzoimidazol-2-yl)-phenyl]-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 47 percent / polyphosphoric acid / xylene / 60 - 150 °C

2: pyridine / 3 h / 20 °C

3: H₂ / Pd/C / methanol; tetrahydrofuran / 16 h / 80 °C

With pyridine; PPA; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; xylene;
DOI:10.1016/j.ejmech.2006.03.014