(R)-methyl 5-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-5-oxopentanoate

Base Information

Chemical Name:(R)-methyl 5-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-5-oxopentanoate
CAS No.:1012060-18-2
Molecular Formula:C₄₈H₅₄ClN₇O₈S₂
Molecular Weight:956.584
Hs Code.:

(R)-methyl 5-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-5-oxopentanoate

Synonyms:(R)-methyl 5-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-5-oxopentanoate

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Chemical Property of (R)-methyl 5-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-5-oxopentanoate

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Technology Process of (R)-methyl 5-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-5-oxopentanoate

There total 1 articles about (R)-methyl 5-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-5-oxopentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.4%

: 406233-35-0
4-(((1R)-3-(dimethylamino)-1-((phenylthio)methyl)propyl)amino)-3-nitrobenzenesulfonamide

: 1012060-17-1
4-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-3-(5-methoxy-5-oxopentanamido)benzoic acid

: 1012060-18-2
(R)-methyl 5-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-5-oxopentanoate

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 25 ℃;

Reference yield: 20.9%

: 1012060-18-2
(R)-methyl 5-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-5-oxopentanoate

: 1012056-44-8
(R)-N¹-(2-(4-((4′-chloro-biphenyl-2-yl)methyl)-piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonyl-carbamoyl)phenyl)-N⁵-hydroxyglutaramide

Guidance literature:: (R)-methyl 5-(2-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)-5-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonylcarbamoyl)phenylamino)-5-oxopentanoate; With hydroxylamine; In methanol; for 0.0833333h; Sonographic reaction;

With acetic acid; In methanol;