trans-8-chloro-3-cyclopropylmethyl-7-[3-chloro-4-(4-hydroxycyclohexylamino)phenyl][1,2,4]triazolo[4,3-a]pyridine

Base Information

Chemical Name:trans-8-chloro-3-cyclopropylmethyl-7-[3-chloro-4-(4-hydroxycyclohexylamino)phenyl][1,2,4]triazolo[4,3-a]pyridine
CAS No.:1255310-64-5
Molecular Formula:C₂₂H₂₄Cl₂N₄O
Molecular Weight:431.365
Hs Code.:

Synonyms:trans-8-chloro-3-cyclopropylmethyl-7-[3-chloro-4-(4-hydroxycyclohexylamino)phenyl][1,2,4]triazolo[4,3-a]pyridine

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Chemical Property of trans-8-chloro-3-cyclopropylmethyl-7-[3-chloro-4-(4-hydroxycyclohexylamino)phenyl][1,2,4]triazolo[4,3-a]pyridine

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Technology Process of trans-8-chloro-3-cyclopropylmethyl-7-[3-chloro-4-(4-hydroxycyclohexylamino)phenyl][1,2,4]triazolo[4,3-a]pyridine

There total 2 articles about trans-8-chloro-3-cyclopropylmethyl-7-[3-chloro-4-(4-hydroxycyclohexylamino)phenyl][1,2,4]triazolo[4,3-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 1254981-17-3
8-chloro-3-(cyclopropylmethyl)-7-iodo-[1,2,4]triazolo[4,3-a]pyridine

: 1152617-68-9
(trans)-4-[2-chloro-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylamino]cyclohexanol

: 1255310-64-5
trans-8-chloro-3-cyclopropylmethyl-7-[3-chloro-4-(4-hydroxycyclohexylamino)phenyl][1,2,4]triazolo[4,3-a]pyridine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate; In 1,4-dioxane; water; at 150 ℃; for 0.166667h; Microwave irradiation;
DOI:10.1021/acs.jmedchem.7b00669