4-[(2-Benzhydryloxy-ethyl)-ethyl-amino]-butyric acid ethyl ester

Base Information

• Chemical Name: 4-[(2-Benzhydryloxy-ethyl)-ethyl-amino]-butyric acid ethyl ester
• CAS No.: 133992-94-6
• Molecular Formula: C₂₃H₃₁NO₃
• Molecular Weight: 369.504
• Mol file: 133992-94-6.mol

Synonyms:4-[(2-Benzhydryloxy-ethyl)-ethyl-amino]-butyric acid ethyl ester

Chemical Property of 4-[(2-Benzhydryloxy-ethyl)-ethyl-amino]-butyric acid ethyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 4-[(2-Benzhydryloxy-ethyl)-ethyl-amino]-butyric acid ethyl ester

There total 1 articles about 4-[(2-Benzhydryloxy-ethyl)-ethyl-amino]-butyric acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

Ethyl 4-bromobutyrate (2969-81-5) + ethyl-(2-benzhydryloxy-ethyl)-amine; hydrochloride (53499-41-5) → 4-[(2-Benzhydryloxy-ethyl)-ethyl-amino]-butyric acid ethyl ester (133992-94-6)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 20h;

DOI:10.1016/0223-5234(91)90214-8

Reference yield:

4-[(2-Benzhydryloxy-ethyl)-ethyl-amino]-butyric acid ethyl ester (133992-94-6) → 4-[(2-Benzhydryloxy-ethyl)-ethyl-amino]-butyric acid (133993-16-5)

Guidance literature:

With sodium hydroxide; In methanol; for 2h; Heating;

DOI:10.1016/0223-5234(91)90214-8

upstream raw materials:

Ethyl 4-bromobutyrate

ethyl-(2-benzhydryloxy-ethyl)-amine; hydrochloride

Downstream raw materials:

4-[(2-Benzhydryloxy-ethyl)-ethyl-amino]-butyric acid