phloroglucinol monobenzenesulfonate

Base Information

• Chemical Name: phloroglucinol monobenzenesulfonate
• CAS No.: 3900-81-0
• Molecular Formula: C₁₂H₁₀O₅S
• Molecular Weight: 266.274
• Mol file: 3900-81-0.mol

Synonyms:phloroglucinol monobenzenesulfonate

Chemical Property of phloroglucinol monobenzenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phloroglucinol monobenzenesulfonate

There total 2 articles about phloroglucinol monobenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

1,3,5-tris<(benzenesulfonyl)oxy>benzene (3840-04-8) → phloroglucinol monobenzenesulfonate (3900-81-0)

Guidance literature:

With potassium hydroxide; In methanol; water; for 0.5h; Heating;

DOI:10.1021/ja00402a039

Reference yield:

→ phloroglucinol monobenzenesulfonate (3900-81-0)

Guidance literature:

Phloroglucinol dibenzolsulphonat, KOH/MeOH/Δ;

DOI:10.1039/jr9650002651

Reference yield:

phloroglucinol monobenzenesulfonate (3900-81-0) → 3,3a-dihydroxy-4-(benzyloxy)-6-methoxy-2,3,3a,8a-tetrahydrofuro<2,3-b>benzofuran (78596-80-2)

Guidance literature:

Multi-step reaction with 8 steps

1: potassium iodide, potassium carbonate / dimethylformamide / 12 h / 25 °C

2: 95 percent / aq. potassium hydroxide / methanol; H₂O / 18 h / Heating

3: 42 percent / HBr / CH₂Cl₂ / 0.33 h / 25 °C

4: 1.) aq. oxalic acid, 2.) aq. sodium hydroxide / 1.) acetone, reflux, 0.5 h, 2.) tetrahydrofuran, 25 deg C, 23.5 h

5: 98 percent / p-toluenesulfonic acid / 3 h / 25 °C

6: 88 percent / hydrogen / 5percent Pd-BaSO₄ / ethyl acetate / 1 h / 25 °C / 760 Torr

7: 98 percent / potassium carbonate / dimethylformamide / 24 h / 25 °C

8: 90 percent / acetic acid / H₂O / 1 h / Heating

With potassium hydroxide; sodium hydroxide; hydrogen bromide; hydrogen; oxalic acid; potassium carbonate; toluene-4-sulfonic acid; acetic acid; potassium iodide; palladium on barium sulfate; In methanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1021/ja00402a039

upstream raw materials:

1,3,5-tris<(benzenesulfonyl)oxy>benzene

Downstream raw materials:

phloroglucinol dibenzyl ether monobenzenesulfonate

1,3-dibenzylphloroglucinol

3,3a-dihydroxy-4-(benzyloxy)-6-methoxy-2,3,3a,8a-tetrahydrofuro<2,3-b>benzofuran

3,3a-acetonide-4-(benzyloxy)-6-hydroxy-2,3,3a,8a-tetrahydrofuro<2,3-b>benzofuran

Refernces