Technology Process of (E)-4-methoxy-2-nitrocinnamyl alcohol
There total 7 articles about (E)-4-methoxy-2-nitrocinnamyl alcohol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
methyl (E)-3-(4′-methoxy-2′-nitrophenyl)acrylate;
With
diisobutylaluminium hydride;
In
toluene;
at 0 - 20 ℃;
for 3h;
With
methanol;
In
toluene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 96 percent / triethylamine / palladium acetate / acetonitrile / 48 h / 100 °C
2: 75 percent / DIBAL / toluene / 0.5 h / 0 °C
With
diisobutylaluminium hydride; triethylamine;
palladium diacetate;
In
toluene; acetonitrile;
1: Heck reaction;
DOI:10.1021/ol016018b
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: c. hydrochloric acid / H2O / 0.25 h / Heating
1.2: sodium nitrite / H2O / 1 h / 0 °C
1.3: 88 percent / potassium iodide / H2O / 2 h / Heating
2.1: 96 percent / triethylamine / palladium acetate / acetonitrile / 48 h / 100 °C
3.1: 75 percent / DIBAL / toluene / 0.5 h / 0 °C
With
hydrogenchloride; diisobutylaluminium hydride; triethylamine;
palladium diacetate;
In
water; toluene; acetonitrile;
2.1: Heck reaction;
DOI:10.1021/ol016018b
