1-nitrosocyclohexyl pivalate

Base Information

• Chemical Name: 1-nitrosocyclohexyl pivalate
• CAS No.: 1264294-14-5
• Molecular Formula: C₁₁H₁₉NO₃
• Molecular Weight: 213.277
• Mol file: 1264294-14-5.mol

Synonyms:1-nitrosocyclohexyl pivalate

Chemical Property of 1-nitrosocyclohexyl pivalate

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of 1-nitrosocyclohexyl pivalate

There total 3 articles about 1-nitrosocyclohexyl pivalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

cyclohexanone-oxime (100-64-1) + bis(tertbutylcarbonyloxy)iodobenzene (57357-20-7) → 1-nitrosocyclohexyl pivalate (1264294-14-5)

Guidance literature:

In dichloromethane; at 0 - 25 ℃; for 0.5h;

DOI:10.1002/anie.202016955

Reference yield: 47.0%

cyclohexanone-oxime (100-64-1) + Trimethylacetic acid (75-98-9) → 1-nitrosocyclohexyl pivalate (1264294-14-5)

Guidance literature:

With lead(IV) tetraacetate; In dichloromethane; at 0 - 20 ℃; for 4h;

DOI:10.1021/jm101432z

Reference yield:

acetoxy-1 nitroso-1 cyclohexane (10259-08-2) → 1-nitrosocyclohexyl pivalate (1264294-14-5)

Guidance literature:

Multi-step reaction with 2 steps

1: N-acetylcystein / methanol / aq. buffer

2: lead(IV) tetraacetate / dichloromethane / 4 h / 0 - 20 °C

With N-acetylcystein; lead(IV) tetraacetate; In methanol; dichloromethane;

DOI:10.1021/jm101432z

upstream raw materials:

cyclohexanone-oxime

Trimethylacetic acid

acetoxy-1 nitroso-1 cyclohexane

bis(tertbutylcarbonyloxy)iodobenzene

Downstream raw materials:

cyclohexanone-oxime

cyclohexanone