4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid lithium salt

Base Information

Chemical Name:4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid lithium salt
CAS No.:1247029-01-1
Molecular Formula:C₁₅H₁₈F₃N₂O₂*Li
Molecular Weight:322.256
Hs Code.:

Synonyms:4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid lithium salt

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Chemical Property of 4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid lithium salt

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Technology Process of 4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid lithium salt

There total 1 articles about 4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid lithium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1247029-00-0
4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid ethyl ester

: 1247029-01-1
4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid lithium salt

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; at 70 ℃; for 0.5h; Microwave irradiation;

Reference yield:

: 1247029-02-2
(4-methylsulfanyl-3-trifluoromethyl-phenyl)-piperidin-4-yl-amine hydrochloride

: 1247029-01-1
4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid lithium salt

: 1247029-03-3
1-[4-(4-methylsulfanyl-3-trifluoromethyl-phenylamino)-piperidin-1-yl]-4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butan-1-one

Guidance literature:: 4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid lithium salt; With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide; for 0.0833333h;

(4-methylsulfanyl-3-trifluoromethyl-phenyl)-piperidin-4-yl-amine hydrochloride; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 3h;

Reference yield:

: 1247029-04-4
3-(piperidin-4-ylamino)-benzonitrile hydrochloride

: 1247029-01-1
4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid lithium salt

: 1247029-05-5
3-(1-{4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyryl}-piperidin-4-ylamino)-benzonitrile

Guidance literature:: 4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid lithium salt; With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide; for 0.0833333h;

3-(piperidin-4-ylamino)-benzonitrile hydrochloride; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 1h;