Enkephalin, ala(2)-pronh2(5)-

Base Information

Chemical Name:Enkephalin, ala(2)-pronh2(5)-
CAS No.:66864-07-1
Molecular Formula:C₂₈H₃₆N₆O₆
Molecular Weight:552.63
Hs Code.:
DSSTox Substance ID:DTXSID70216999
Wikidata:Q83093363
Mol file:66864-07-1.mol

Synonyms:2-Ala-5-ProNH2-enkephalin;enkephalin, Ala(2)-ProNH2(5)-;enkephalin, alanyl(2)-prolinamide(5)-;enkephalinamide, Ala(2)-Pro(5)-;Wy 42,186;Wy-42,186

Suppliers and Price of Enkephalin, ala(2)-pronh2(5)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Enkephalin, ala(2)-pronh2(5)-

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:1023.7°Cat760mmHg
Flash Point:572.9°C
PSA：208.41000
Density:1.314g/cm³
LogP:3.39550
XLogP3:0
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:12
Exact Mass:552.26963289
Heavy Atom Count:40
Complexity:902

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)NCC(=O)NC(CC1=CC=CC=C1)C(=O)N2CCCC2C(=O)N)NC(=O)C(CC3=CC=C(C=C3)O)N
Isomeric SMILES:C[C@H](C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N2CCC[C@H]2C(=O)N)NC(=O)[C@H](CC3=CC=C(C=C3)O)N

Technology Process of Enkephalin, ala(2)-pronh2(5)-

There total 9 articles about Enkephalin, ala(2)-pronh2(5)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Boc Tyr D_.Ala Gly Phe Pro NH₂

: 66864-07-1
Tyr D_.Ala Gly Phe Pro NH₂

Guidance literature:: With hydrogenchloride; acetic acid; In various solvent(s); for 90h;

Reference yield:

: 71591-34-9
N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanine

: 66864-07-1
Tyr D_.Ala Gly Phe Pro NH₂

Guidance literature:: Multi-step reaction with 7 steps

1: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / formamide / 10 h. 0 deg C, 10 h. room temp.

2: H₂O, NaOH / methanol

3: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide

4: H₂O, NaOH / methanol

5: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide

6: NH₃ / methanol

7: HCl, acetic acid / various solvent(s) / 90 h

With hydrogenchloride; sodium hydroxide; ammonia; water; benzotriazol-1-ol; acetic acid; triethylamine; dicyclohexyl-carbodiimide; In methanol; formamide; N,N-dimethyl-formamide;

Reference yield:

: 64410-47-5,79225-08-4
N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanylglycine

: 66864-07-1
Tyr D_.Ala Gly Phe Pro NH₂

Guidance literature:: Multi-step reaction with 5 steps

1: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide

2: H₂O, NaOH / methanol

3: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide

4: NH₃ / methanol

5: HCl, acetic acid / various solvent(s) / 90 h

With hydrogenchloride; sodium hydroxide; ammonia; water; benzotriazol-1-ol; acetic acid; triethylamine; dicyclohexyl-carbodiimide; In methanol; N,N-dimethyl-formamide;