Thiamylal

Base Information Edit

Chemical Name:Thiamylal
CAS No.:77-27-0
Deprecated CAS:1340-07-4,7187-63-5
Molecular Formula:C12H18 N2 O2 S
Molecular Weight:254.353
Hs Code.:2933530015
European Community (EC) Number:201-018-3
NSC Number:120815
UNII:01T23W89FR
DSSTox Substance ID:DTXSID3048441
Nikkaji Number:J38.391K
Wikipedia:Thiamylal
Wikidata:Q906102
NCI Thesaurus Code:C66596
Pharos Ligand ID:UK39A1HAYYJ2
Metabolomics Workbench ID:43375
ChEMBL ID:CHEMBL440
Mol file:77-27-0.mol

Synonyms:Sodium, Thiamylal;Surital;Thiamylal;Thiamylal Sodium;Thioquinalbarbitone

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Thiamylal Edit

Chemical Property:

Melting Point:132-133°
Refractive Index:1.5510 (estimate)
PKA:7.01±0.40(Predicted)
PSA：90.29000
Density:1.16g/cm³
LogP:2.17360
Water Solubility.:1.298g/L(25 oC)
XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:254.10889899
Heavy Atom Count:17
Complexity:346

Purity/Quality:

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 23/24/25
Safety Statements: 36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCCC(C)C1(C(=O)NC(=S)NC1=O)CC=C
Recent NIPH Clinical Trials:The Effects of Intravenous Anesthetics on QT interval during Anesthetic Induction with Desflurane
Uses Thiamylal is a barbiturate derivative with sedative, anticonvulsant and hypnotic effects. Thiamylal is used for induction in surgical anaesthesia as well as an anticonvulsant to counteract side effects from other anaesthetics. Thiamylal is a Controlled Substance.

Technology Process of Thiamylal

There total 4 articles about Thiamylal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: