Erythromycin, 9-deoxy-9-(propylamino)-

Base Information

• Chemical Name: Erythromycin, 9-deoxy-9-(propylamino)-
• CAS No.: 119904-03-9
• Molecular Formula: C₄₀H₇₆N₂O₁₂
• Molecular Weight: 777.05
• UNII: B83RU5KE3D
• Wikidata: Q27274488
• ChEMBL ID: CHEMBL1697688
• Mol file: 119904-03-9.mol

Synonyms:9-N-(1-propyl)erythromyclamine;LY 281389;LY-281389;LY281389

Chemical Property of Erythromycin, 9-deoxy-9-(propylamino)-

Chemical Property:

• Vapor Pressure: 5.42E-32mmHg at 25°C
• Boiling Point: 830.4°Cat760mmHg
• Flash Point: 456°C
• PSA: 188.87000
• Density: 1.16g/cm³
• LogP: 2.97560
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 14
• Rotatable Bond Count: 10
• Exact Mass: 776.53982586
• Heavy Atom Count: 54
• Complexity: 1180

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCNC1C(CC(C(C(C(C(C(=O)OC(C(C(C1C)O)(C)O)CC)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C
• Isomeric SMILES: CCCN[C@H]1[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O[C@@H]([C@@]([C@@H]([C@H]1C)O)(C)O)CC)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C

Technology Process of Erythromycin, 9-deoxy-9-(propylamino)-

There total 1 articles about Erythromycin, 9-deoxy-9-(propylamino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

erythromycylamine (26116-56-3) + propionaldehyde (123-38-6) → 9-N-(1-propyl)erythromycylamine (119904-03-9)

Guidance literature:

With sodium phosphate buffer; sodium cyanoborohydride; In acetonitrile; for 3h; Ambient temperature;

DOI:10.1021/jm00173a028

upstream raw materials:

erythromycylamine

propionaldehyde

Refernces