[(E)-4-Methyl-7-(2-methyl-[1,3]dioxolan-2-yl)-hept-4-enyl]-triphenyl-phosphonium; iodide

Base Information

• Chemical Name: [(E)-4-Methyl-7-(2-methyl-[1,3]dioxolan-2-yl)-hept-4-enyl]-triphenyl-phosphonium; iodide
• CAS No.: 4586-88-3
• Molecular Formula: C₃₀H₃₆O₂P*I
• Molecular Weight: 586.493
• Mol file: 4586-88-3.mol

Synonyms:[(E)-4-Methyl-7-(2-methyl-[1,3]dioxolan-2-yl)-hept-4-enyl]-triphenyl-phosphonium; iodide

Chemical Property of [(E)-4-Methyl-7-(2-methyl-[1,3]dioxolan-2-yl)-hept-4-enyl]-triphenyl-phosphonium; iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(E)-4-Methyl-7-(2-methyl-[1,3]dioxolan-2-yl)-hept-4-enyl]-triphenyl-phosphonium; iodide

There total 4 articles about [(E)-4-Methyl-7-(2-methyl-[1,3]dioxolan-2-yl)-hept-4-enyl]-triphenyl-phosphonium; iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.4%

triphenylphosphine (603-35-0) + 2-methyl-2-(7-chloro-4-methyl-3-heptenyl)-1,3-dioxolane (162827-16-9) → [(E)-4-Methyl-7-(2-methyl-[1,3]dioxolan-2-yl)-hept-4-enyl]-triphenyl-phosphonium; iodide (4586-88-3)

Guidance literature:

With sodium iodide; In acetonitrile; at 80 ℃; for 23h;

DOI:10.1248/cpb.42.2154

Reference yield:

1-chloro-4-(1,3-dioxolane)-n-pentane (5978-08-5) → [(E)-4-Methyl-7-(2-methyl-[1,3]dioxolan-2-yl)-hept-4-enyl]-triphenyl-phosphonium; iodide (4586-88-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 83.8 percent / NaI / acetonitrile / 44 h / 80 °C

2: 1.) BuLi / 1.) hexane, THF, RT, 1 h, 2.) hexane, THF, a) -78 deg C, 0.5 h, b) RT, 18 h

3: 91.4 percent / NaI / acetonitrile / 23 h / 80 °C

With n-butyllithium; sodium iodide; In acetonitrile;

DOI:10.1248/cpb.42.2154

Reference yield:

(3-(2-methyl-1,3-dioxolan-2-yl)propyl)triphenylphosphonium iodide (21955-58-8) → [(E)-4-Methyl-7-(2-methyl-[1,3]dioxolan-2-yl)-hept-4-enyl]-triphenyl-phosphonium; iodide (4586-88-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) BuLi / 1.) hexane, THF, RT, 1 h, 2.) hexane, THF, a) -78 deg C, 0.5 h, b) RT, 18 h

2: 91.4 percent / NaI / acetonitrile / 23 h / 80 °C

With n-butyllithium; sodium iodide; In acetonitrile;

DOI:10.1248/cpb.42.2154

upstream raw materials:

triphenylphosphine

2-methyl-2-(7-chloro-4-methyl-3-heptenyl)-1,3-dioxolane

1-chloro-4-(1,3-dioxolane)-n-pentane

(3-(2-methyl-1,3-dioxolan-2-yl)propyl)triphenylphosphonium iodide