4-nitrobenzyl(1S,5R,6S)-2-(7-formyl-5-methylimidazo[5,1-b]thiazol-2-yl)-6-((1R)-1-hydroxyethyl)-1-methyl-1-carbapen-2-em-3-carboxylate

Base Information

Chemical Name:4-nitrobenzyl(1S,5R,6S)-2-(7-formyl-5-methylimidazo[5,1-b]thiazol-2-yl)-6-((1R)-1-hydroxyethyl)-1-methyl-1-carbapen-2-em-3-carboxylate
CAS No.:258840-58-3
Molecular Formula:C₂₄H₂₂N₄O₇S
Molecular Weight:510.527
Hs Code.:

Synonyms:4-nitrobenzyl(1S,5R,6S)-2-(7-formyl-5-methylimidazo[5,1-b]thiazol-2-yl)-6-((1R)-1-hydroxyethyl)-1-methyl-1-carbapen-2-em-3-carboxylate

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Chemical Property of 4-nitrobenzyl(1S,5R,6S)-2-(7-formyl-5-methylimidazo[5,1-b]thiazol-2-yl)-6-((1R)-1-hydroxyethyl)-1-methyl-1-carbapen-2-em-3-carboxylate

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Technology Process of 4-nitrobenzyl(1S,5R,6S)-2-(7-formyl-5-methylimidazo[5,1-b]thiazol-2-yl)-6-((1R)-1-hydroxyethyl)-1-methyl-1-carbapen-2-em-3-carboxylate

There total 7 articles about 4-nitrobenzyl(1S,5R,6S)-2-(7-formyl-5-methylimidazo[5,1-b]thiazol-2-yl)-6-((1R)-1-hydroxyethyl)-1-methyl-1-carbapen-2-em-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 258840-57-2
4-Nitrobenzyl(1S,5R,6S)-6-((1R)-1-hydroxyethyl)-2-(7-hydroxymethyl-5-methylimidazo-[5,1-b]thiazol-2-yl)-1-methyl-1-carbapen-2-em-3-carboxylate

: 258840-58-3
4-nitrobenzyl(1S,5R,6S)-2-(7-formyl-5-methylimidazo[5,1-b]thiazol-2-yl)-6-((1R)-1-hydroxyethyl)-1-methyl-1-carbapen-2-em-3-carboxylate

Guidance literature:: With manganese dioxide; In dichloromethane;

Reference yield:

: 165666-84-2
5-methylimidazo[5,1-b]thiazole

: 258840-58-3
4-nitrobenzyl(1S,5R,6S)-2-(7-formyl-5-methylimidazo[5,1-b]thiazol-2-yl)-6-((1R)-1-hydroxyethyl)-1-methyl-1-carbapen-2-em-3-carboxylate

Guidance literature:: Multi-step reaction with 6 steps

1: sodium hydroxide; trichlorophosphate / dichloromethane; N,N-dimethyl-formamide

2: sodium hydrogencarbonate / methanol; water; N,N-dimethyl-formamide

5: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran

6: manganese dioxide / dichloromethane

With sodium hydroxide; manganese dioxide; tetrabutyl ammonium fluoride; sodium hydrogencarbonate; acetic acid; trichlorophosphate; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

: 258839-89-3
7-formyl-5-methylimidazo[5,1-b]thiazole

: 258840-58-3
4-nitrobenzyl(1S,5R,6S)-2-(7-formyl-5-methylimidazo[5,1-b]thiazol-2-yl)-6-((1R)-1-hydroxyethyl)-1-methyl-1-carbapen-2-em-3-carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: sodium hydrogencarbonate / methanol; water; N,N-dimethyl-formamide

4: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran

5: manganese dioxide / dichloromethane

With manganese dioxide; tetrabutyl ammonium fluoride; sodium hydrogencarbonate; acetic acid; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;