5-O-(2,4-di-O-acetyl-3-O-(3-hydroxypropyl)-6-deoxy-β-D-glucopyranosyl)-6,3',4'-tri-O-benzyl-1,3,2',6'-tetraazidoneamine

Base Information

Chemical Name:5-O-(2,4-di-O-acetyl-3-O-(3-hydroxypropyl)-6-deoxy-β-D-glucopyranosyl)-6,3',4'-tri-O-benzyl-1,3,2',6'-tetraazidoneamine
CAS No.:675616-56-5
Molecular Formula:C₄₆H₅₆N₁₂O₁₃
Molecular Weight:985.023
Hs Code.:

Synonyms:5-O-(2,4-di-O-acetyl-3-O-(3-hydroxypropyl)-6-deoxy-β-D-glucopyranosyl)-6,3',4'-tri-O-benzyl-1,3,2',6'-tetraazidoneamine

Suppliers and Price of 5-O-(2,4-di-O-acetyl-3-O-(3-hydroxypropyl)-6-deoxy-β-D-glucopyranosyl)-6,3',4'-tri-O-benzyl-1,3,2',6'-tetraazidoneamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-O-(2,4-di-O-acetyl-3-O-(3-hydroxypropyl)-6-deoxy-β-D-glucopyranosyl)-6,3',4'-tri-O-benzyl-1,3,2',6'-tetraazidoneamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-O-(2,4-di-O-acetyl-3-O-(3-hydroxypropyl)-6-deoxy-β-D-glucopyranosyl)-6,3',4'-tri-O-benzyl-1,3,2',6'-tetraazidoneamine

There total 5 articles about 5-O-(2,4-di-O-acetyl-3-O-(3-hydroxypropyl)-6-deoxy-β-D-glucopyranosyl)-6,3',4'-tri-O-benzyl-1,3,2',6'-tetraazidoneamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 675616-55-4
5-O-(2,4-di-O-acetyl-3-O-allyl-6-deoxy-β-D-glucopyranosyl)-6,3',4'-tri-O-benzyl-1,3,2',6'-tetraazidoneamine

: 675616-56-5
5-O-(2,4-di-O-acetyl-3-O-(3-hydroxypropyl)-6-deoxy-β-D-glucopyranosyl)-6,3',4'-tri-O-benzyl-1,3,2',6'-tetraazidoneamine

Guidance literature:: 5-O-(2,4-di-O-acetyl-3-O-allyl-6-deoxy-β-D-glucopyranosyl)-6,3',4'-tri-O-benzyl-1,3,2',6'-tetraazidoneamine; With ammonia; In tetrahydrofuran; at 20 ℃; for 3h;

With sodium hydroxide; dihydrogen peroxide; In tetrahydrofuran; water;
DOI:10.1021/jo035290r

Reference yield:

: 134311-53-8
3-O-allyl-6-deoxy-1,2-O-isopropylidene-α-D-glucofuranose

: 675616-56-5
5-O-(2,4-di-O-acetyl-3-O-(3-hydroxypropyl)-6-deoxy-β-D-glucopyranosyl)-6,3',4'-tri-O-benzyl-1,3,2',6'-tetraazidoneamine

Guidance literature:: Multi-step reaction with 5 steps

1.1: TFA; AcOH / H₂O / 1 h / 70 °C

1.2: 96 percent / H₂SO₄ / 0 °C

2.1: hydrazine acetate / dimethylformamide / 20 °C

3.1: DBU / CH₂Cl₂ / 20 °C

4.1: 62 percent / BF₃*OEt₂ / CH₂Cl₂ / -50 °C

5.1: NH₃ / tetrahydrofuran / 3 h / 20 °C

5.2: 69 percent / NaOH; H₂O₂ / tetrahydrofuran; H₂O

With boron trifluoride diethyl etherate; ammonia; hydrazinium monoacetate; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jo035290r

Reference yield:

: Acetic acid (3R,4S,5R,6R)-5-acetoxy-4-allyloxy-2-hydroxy-6-methyl-tetrahydro-pyran-3-yl ester

: 675616-56-5
5-O-(2,4-di-O-acetyl-3-O-(3-hydroxypropyl)-6-deoxy-β-D-glucopyranosyl)-6,3',4'-tri-O-benzyl-1,3,2',6'-tetraazidoneamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: DBU / CH₂Cl₂ / 20 °C

2.1: 62 percent / BF₃*OEt₂ / CH₂Cl₂ / -50 °C

3.1: NH₃ / tetrahydrofuran / 3 h / 20 °C

3.2: 69 percent / NaOH; H₂O₂ / tetrahydrofuran; H₂O

With boron trifluoride diethyl etherate; ammonia; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo035290r