N-benzyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-N-methyl-succinamic acid allyl ester

Base Information

• Chemical Name: N-benzyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-N-methyl-succinamic acid allyl ester
• CAS No.: 1026627-28-0
• Molecular Formula: C₃₀H₃₀N₂O₅
• Molecular Weight: 498.579
• Mol file: 1026627-28-0.mol

Synonyms:N-benzyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-N-methyl-succinamic acid allyl ester

Chemical Property of N-benzyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-N-methyl-succinamic acid allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-N-methyl-succinamic acid allyl ester

There total 2 articles about N-benzyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-N-methyl-succinamic acid allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl-methyl-amine (103-67-3) + 3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-isobutoxycarbonyloxy-4-oxo-butyric acid allyl ester → N-benzyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-N-methyl-succinamic acid allyl ester (1026627-28-0)

Guidance literature:

With 4-methyl-morpholine; In tetrahydrofuran; at 0 - 20 ℃; for 4h;

DOI:10.1039/b100401h

Reference yield:

N-alpha-(9-fluorenylmethyloxycarbonyl)-D-aspartic acid beta-allyl ester (177609-12-0) → N-benzyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-N-methyl-succinamic acid allyl ester (1026627-28-0)

Guidance literature:

Multi-step reaction with 2 steps

1: NMM / tetrahydrofuran / 0.08 h / -15 °C

2: NMM / tetrahydrofuran / 4 h / 0 - 20 °C

With 4-methyl-morpholine; In tetrahydrofuran;

DOI:10.1039/b100401h

Reference yield:

N-benzyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-N-methyl-succinamic acid allyl ester (1026627-28-0) → N-benzyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-N-methyl-succinamic acid

Guidance literature:

With phenylsilane; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In dichloromethane; at 20 ℃;

DOI:10.1039/b100401h

upstream raw materials:

benzyl-methyl-amine

N-alpha-(9-fluorenylmethyloxycarbonyl)-D-aspartic acid beta-allyl ester