9-<5-O-(monomethoxytrityl)-3-deoxy-3-S-(5-nitropyridyl-2-disulfanyl)-2-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl>hypoxanthine

Base Information

Chemical Name:9-<5-O-(monomethoxytrityl)-3-deoxy-3-S-(5-nitropyridyl-2-disulfanyl)-2-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl>hypoxanthine
CAS No.:174467-02-8
Molecular Formula:C₄₁H₄₄N₆O₇S₂Si
Molecular Weight:825.054
Hs Code.:

Synonyms:9-<5-O-(monomethoxytrityl)-3-deoxy-3-S-(5-nitropyridyl-2-disulfanyl)-2-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl>hypoxanthine

Suppliers and Price of 9-<5-O-(monomethoxytrityl)-3-deoxy-3-S-(5-nitropyridyl-2-disulfanyl)-2-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl>hypoxanthine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 9-<5-O-(monomethoxytrityl)-3-deoxy-3-S-(5-nitropyridyl-2-disulfanyl)-2-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl>hypoxanthine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 9-<5-O-(monomethoxytrityl)-3-deoxy-3-S-(5-nitropyridyl-2-disulfanyl)-2-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl>hypoxanthine

There total 7 articles about 9-<5-O-(monomethoxytrityl)-3-deoxy-3-S-(5-nitropyridyl-2-disulfanyl)-2-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl>hypoxanthine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 69739-34-0
t-butyldimethylsiyl triflate

: 174467-01-7
9-[(2R,3S,4S,5R)-3-Hydroxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-4-(5-nitro-pyridin-2-yldisulfanyl)-tetrahydro-furan-2-yl]-1,9-dihydro-purin-6-one

: 174467-02-8
9-<5-O-(monomethoxytrityl)-3-deoxy-3-S-(5-nitropyridyl-2-disulfanyl)-2-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl>hypoxanthine

Guidance literature:: With pyridine; for 4h;
DOI:10.1021/ja9616903

Reference yield:

: 31766-13-9
2',3'-anhydroinosine

: 174467-02-8
9-<5-O-(monomethoxytrityl)-3-deoxy-3-S-(5-nitropyridyl-2-disulfanyl)-2-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl>hypoxanthine

Guidance literature:: Multi-step reaction with 5 steps

1: 60 percent / NaI, BF₃*Et₂O / acetonitrile / 1 h / Ambient temperature

2: 65 percent / pyridine

3: 50 percent / dimethylformamide / 48 h / 40 °C

4: 1.) NaOH / 1.) MeOH, 2 h, 2.) 30 min

5: 88 percent / pyridine / 4 h

With pyridine; sodium hydroxide; boron trifluoride diethyl etherate; sodium iodide; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ja9616903

Reference yield:

: 54883-90-8
9-(3-deoxy-3-iodo-β-D-xylofuranosyl)hypoxanthine

: 174467-02-8
9-<5-O-(monomethoxytrityl)-3-deoxy-3-S-(5-nitropyridyl-2-disulfanyl)-2-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl>hypoxanthine

Guidance literature:: Multi-step reaction with 4 steps

1: 65 percent / pyridine

2: 50 percent / dimethylformamide / 48 h / 40 °C

3: 1.) NaOH / 1.) MeOH, 2 h, 2.) 30 min

4: 88 percent / pyridine / 4 h

With pyridine; sodium hydroxide; In N,N-dimethyl-formamide;
DOI:10.1021/ja9616903