(tert-Butyl-dimethyl-silanyl)-(methyl-diphenyl-silanyl)-ethenone

Base Information

• Chemical Name: (tert-Butyl-dimethyl-silanyl)-(methyl-diphenyl-silanyl)-ethenone
• CAS No.: 181135-72-8
• Molecular Formula: C₂₁H₂₈OSi₂
• Molecular Weight: 352.624
• Mol file: 181135-72-8.mol

Synonyms:(tert-Butyl-dimethyl-silanyl)-(methyl-diphenyl-silanyl)-ethenone

Chemical Property of (tert-Butyl-dimethyl-silanyl)-(methyl-diphenyl-silanyl)-ethenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (tert-Butyl-dimethyl-silanyl)-(methyl-diphenyl-silanyl)-ethenone

There total 4 articles about (tert-Butyl-dimethyl-silanyl)-(methyl-diphenyl-silanyl)-ethenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

t-butyldimethylsiyl triflate (69739-34-0) + (methyl-diphenyl-silanyl)-trimethylsilanyl-ethenone (180922-90-1) → (tert-Butyl-dimethyl-silanyl)-(methyl-diphenyl-silanyl)-ethenone (181135-72-8)

Guidance literature:

(methyl-diphenyl-silanyl)-trimethylsilanyl-ethenone; With potassium tert-butylate; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at 0 ℃; for 1h;

t-butyldimethylsiyl triflate; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at 20 ℃; for 2h;

DOI:10.1055/s-2002-32975

Reference yield: 30.0%

chloromethyldiphenylsilane (144-79-6) + tert-butyldimethylsilylketene (104992-44-1) → (tert-Butyl-dimethyl-silanyl)-(methyl-diphenyl-silanyl)-ethenone (181135-72-8)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; 1.) -100 deg C, 30 min, 2.) -100 deg C, 1 h; -70 deg C, 3 h;

Reference yield:

bis(trimethylsilyl)ketene (19061-00-8) → (tert-Butyl-dimethyl-silanyl)-(methyl-diphenyl-silanyl)-ethenone (181135-72-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: tBuOK / tetrahydrofuran; hexamethylphosphoric acid triamide / 1 h / 0 °C

1.2: 75 percent / tetrahydrofuran; hexamethylphosphoric acid triamide / 2 h / 20 °C

2.1: tBuOK / tetrahydrofuran; hexamethylphosphoric acid triamide / 1 h / 0 °C

2.2: 79 percent / tetrahydrofuran; hexamethylphosphoric acid triamide / 2 h / 20 °C

With potassium tert-butylate; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide;

DOI:10.1055/s-2002-32975

upstream raw materials:

chloromethyldiphenylsilane

tert-butyldimethylsilylketene

t-butyldimethylsiyl triflate

(methyl-diphenyl-silanyl)-trimethylsilanyl-ethenone