(2R,3S,5R)-3-benzyloxy-2-benzyloxymethyl-5-(trimethylsilylethynyl)tetrahydrofuran

Base Information

Chemical Name:(2R,3S,5R)-3-benzyloxy-2-benzyloxymethyl-5-(trimethylsilylethynyl)tetrahydrofuran
CAS No.:503057-02-1
Molecular Formula:C₂₄H₃₀O₃Si
Molecular Weight:394.586
Hs Code.:

Synonyms:(2R,3S,5R)-3-benzyloxy-2-benzyloxymethyl-5-(trimethylsilylethynyl)tetrahydrofuran

Suppliers and Price of (2R,3S,5R)-3-benzyloxy-2-benzyloxymethyl-5-(trimethylsilylethynyl)tetrahydrofuran

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3S,5R)-3-benzyloxy-2-benzyloxymethyl-5-(trimethylsilylethynyl)tetrahydrofuran

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Technology Process of (2R,3S,5R)-3-benzyloxy-2-benzyloxymethyl-5-(trimethylsilylethynyl)tetrahydrofuran

There total 6 articles about (2R,3S,5R)-3-benzyloxy-2-benzyloxymethyl-5-(trimethylsilylethynyl)tetrahydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 503056-84-6
(2R,3S,5R)-1,3-bis(benzyloxy)-7-(trimethylsilyl)hept-6-yne-2,5-diol

: 503057-02-1
(2R,3S,5R)-3-benzyloxy-2-benzyloxymethyl-5-(trimethylsilylethynyl)tetrahydrofuran

Guidance literature:: (2R,3S,5R)-1,3-bis(benzyloxy)-7-(trimethylsilyl)hept-6-yne-2,5-diol; With dicobalt octacarbonyl; In dichloromethane;

With trifluorormethanesulfonic acid; In dichloromethane; at 25 ℃;

With iodine; Further stages.;
DOI:10.1021/ol027210w

Reference yield: 90.0%

: (2R,3S)-1,3-Bis-benzyloxy-7-trimethylsilanyl-hept-6-yne-2,5-diol

: 503057-02-1
(2R,3S,5R)-3-benzyloxy-2-benzyloxymethyl-5-(trimethylsilylethynyl)tetrahydrofuran

: (2R,3S,5S)-3-benzyloxy-2-benzyloxymethyl-5-(trimethylsilylethynyl)tetrahydrofuran

Guidance literature:: (2R,3S)-1,3-Bis-benzyloxy-7-trimethylsilanyl-hept-6-yne-2,5-diol; With dicobalt octacarbonyl; trifluorormethanesulfonic acid; In dichloromethane; at 20 ℃; for 6h;

With iodine; triethylamine; In dichloromethane; at 20 ℃; for 1h; Further stages.;
DOI:10.1021/ol027210w