(5R,9R,10R,11S,13R,E)-15,15-diisopropyl-13-(5-(4-methoxybenzyloxy)pentyl)-11-(methoxymethoxy)-7,10,16-trimethyl-5-propyl-2,4,14-trioxa-15-silaheptadec-7-en-9-ol

Base Information

• Chemical Name: (5R,9R,10R,11S,13R,E)-15,15-diisopropyl-13-(5-(4-methoxybenzyloxy)pentyl)-11-(methoxymethoxy)-7,10,16-trimethyl-5-propyl-2,4,14-trioxa-15-silaheptadec-7-en-9-ol
• CAS No.: 1018689-70-7
• Molecular Formula: C₄₀H₇₄O₈Si
• Molecular Weight: 711.108
• Mol file: 1018689-70-7.mol

Synonyms:(5R,9R,10R,11S,13R,E)-15,15-diisopropyl-13-(5-(4-methoxybenzyloxy)pentyl)-11-(methoxymethoxy)-7,10,16-trimethyl-5-propyl-2,4,14-trioxa-15-silaheptadec-7-en-9-ol

Chemical Property of (5R,9R,10R,11S,13R,E)-15,15-diisopropyl-13-(5-(4-methoxybenzyloxy)pentyl)-11-(methoxymethoxy)-7,10,16-trimethyl-5-propyl-2,4,14-trioxa-15-silaheptadec-7-en-9-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (5R,9R,10R,11S,13R,E)-15,15-diisopropyl-13-(5-(4-methoxybenzyloxy)pentyl)-11-(methoxymethoxy)-7,10,16-trimethyl-5-propyl-2,4,14-trioxa-15-silaheptadec-7-en-9-ol

There total 2 articles about (5R,9R,10R,11S,13R,E)-15,15-diisopropyl-13-(5-(4-methoxybenzyloxy)pentyl)-11-(methoxymethoxy)-7,10,16-trimethyl-5-propyl-2,4,14-trioxa-15-silaheptadec-7-en-9-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(5R,10S,11S,13R,E)-15,15-diisopropyl-13-(5-(4-methoxybenzyloxy)pentyl)-11-(methoxymethoxy)-7,10,16-trimethyl-5-propyl-2,4,14-trioxa-15-silaheptadec-7-en-9-one (1018689-80-9) → (5R,9R,10R,11S,13R,E)-15,15-diisopropyl-13-(5-(4-methoxybenzyloxy)pentyl)-11-(methoxymethoxy)-7,10,16-trimethyl-5-propyl-2,4,14-trioxa-15-silaheptadec-7-en-9-ol (1018689-70-7) + (5R,9S,10R,11R,13R,E)-15,15-diisopropyl-13-(5-(4-methoxybenzyloxy)pentyl)-9-(methoxymethoxy)-7,10,16-trimethyl-5-propyl-2,4,14-trioxa-15-silaheptadec-7-en-11-ol

Guidance literature:

With diisobutylaluminium hydride; lithium iodide; In diethyl ether; at -78 - 0 ℃; optical yield given as %de;

DOI:10.1021/ol8001865

Reference yield:

(R,E)-1-iodo-4-(methoxymethoxy)-2-methylhept-1-ene (1018689-59-2) + C30H54O6Si (1018689-69-4) → (5R,9R,10R,11S,13R,E)-15,15-diisopropyl-13-(5-(4-methoxybenzyloxy)pentyl)-11-(methoxymethoxy)-7,10,16-trimethyl-5-propyl-2,4,14-trioxa-15-silaheptadec-7-en-9-ol (1018689-70-7) + (5R,9S,10R,11R,13R,E)-15,15-diisopropyl-13-(5-(4-methoxybenzyloxy)pentyl)-9-(methoxymethoxy)-7,10,16-trimethyl-5-propyl-2,4,14-trioxa-15-silaheptadec-7-en-11-ol

Guidance literature:

(R,E)-1-iodo-4-(methoxymethoxy)-2-methylhept-1-ene; With tert.-butyl lithium; In diethyl ether; pentane; at -78 - 0 ℃; for 0.416667h;

C₃₀H₅₄O₆Si; In diethyl ether; pentane; at -78 ℃; for 1h;

DOI:10.1021/ol8001865

Reference yield: 96.0%

(5R,9R,10R,11S,13R,E)-15,15-diisopropyl-13-(5-(4-methoxybenzyloxy)pentyl)-11-(methoxymethoxy)-7,10,16-trimethyl-5-propyl-2,4,14-trioxa-15-silaheptadec-7-en-9-ol (1018689-70-7) + chloromethyl methyl ether (107-30-2) → C42H78O9Si (1018689-81-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In 1,2-dichloro-ethane; at 20 - 50 ℃; Inert atmosphere;

DOI:10.1021/ol8001865

upstream raw materials:

(R,E)-1-iodo-4-(methoxymethoxy)-2-methylhept-1-ene

C₃₀H₅₄O₆Si

(5R,10S,11S,13R,E)-15,15-diisopropyl-13-(5-(4-methoxybenzyloxy)pentyl)-11-(methoxymethoxy)-7,10,16-trimethyl-5-propyl-2,4,14-trioxa-15-silaheptadec-7-en-9-one

Downstream raw materials:

C₄₂H₇₈O₉Si